rs9674544

This variant is located in the IGF2BP1 gene.

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GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

odontogenesis

Pillas D et al. “Genome-wide association study reveals multiple loci associated with primary tooth development during infancy.” Plos Genetics 6(2):e1000856 (2010)

Allele G

OR —

p 2.0e-8

N 5,752

Large GWAS

European

About IGF2BP1

This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and regulating their translation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

View all IGF2BP1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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