rs9719620

This is a downstream gene variant variant in the MKLN1 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

alopecia

Hagenaars SP et al. “Genetic prediction of male pattern baldness.” Plos Genetics 13(2):e1006594 (2017)

Allele C

OR —

β 0.037

p 2.0e-9

N 52,874

Large GWAS

European

androgenetic alopecia

Pirastu N et al. “GWAS for male-pattern baldness identifies 71 susceptibility loci explaining 38% of the risk.” Nature Communications 8(1):1584 (2017)

Allele T

OR 0.08

p 3.0e-8

N 43,590

Large GWAS

European

About MKLN1

Muskelin is an intracellular protein that acts as a mediator of cell spreading and cytoskeletal responses to the extracellular matrix component thrombospondin I (MIM 188060) (Adams et al., 1998 [PubMed 9724633]).[supplied by OMIM, Mar 2008]

View all MKLN1 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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