rs9825041
This is a intron variant variant in the LARS2 gene.
▶Research that mentions this SNP (1)
▶Genetic association analysis of LARS2 with type 2 diabetesAssociationN=35,715Reiling E. et al.(2010)· Diabetologia
Large-scale genetic association study testing the LARS2 gene (mitochondrial leucyl-tRNA synthetase) for type 2 diabetes susceptibility in 35,715 European-descent participants. The authors failed to replicate the previously reported association of the H324Q variant (rs71645922) with type 2 diabetes (OR 0.99, p=0.78) and found no association with common LARS2 variants, concluding that LARS2 does not play a significant role in type 2 diabetes susceptibility.
About LARS2
This gene encodes a class 1 aminoacyl-tRNA synthetase, mitochondrial leucyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. [provided by RefSeq, Jul 2008]
View all LARS2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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