rs9924561
This is a downstream gene variant variant in the FAM234A gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
hemoglobin measurement
Kowalski MH et al. “Use of >100,000 NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium whole genome sequences improves imputation quality and detection of rare variant associations in admixed African and Hispanic/Latino populations.” Plos Genetics 15(12):e1008500 (2019)
Allele T
OR 0.24
p 2.0e-49
N 43,187
Major Consortium StudyLarge GWAS
multi-ancestry
mean corpuscular hemoglobin
Hodonsky CJ et al. “Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.” Plos Genetics 13(4):e1006760 (2017)
Allele T
OR 1.72
p 4.0e-42
N 12,502
Large GWAS
Hispanic or Latin American
Ding K et al. “Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.” G3 (bethesda, Md.) 3(7):1061-8 (2013)
Allele T
OR 1.56
p 8.0e-36
N 1,904
Large GWAS
African American or Afro-Caribbean
erythrocyte volume
Hodonsky CJ et al. “Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.” Plos Genetics 13(4):e1006760 (2017)
Allele T
OR 3.88
p 6.0e-30
N 12,502
Large GWAS
Hispanic or Latin American
Vuckovic D et al. “The Polygenic and Monogenic Basis of Blood Traits and Diseases.” Cell 182(5):1214-1231.e11 (2020)
Allele T
OR 0.89
p 6.0e-14
N 408,112
Large GWAS
European
Ding K et al. “Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.” G3 (bethesda, Md.) 3(7):1061-8 (2013)
Allele T
OR 3.57
p 5.0e-29
N 1,904
Large GWAS
African American or Afro-Caribbean
mean corpuscular hemoglobin concentration
Ding K et al. “Genetic variants that confer resistance to malaria are associated with red blood cell traits in African-Americans: an electronic medical record-based genome-wide association study.” G3 (bethesda, Md.) 3(7):1061-8 (2013)
Allele T
OR 0.47
p 9.0e-17
N 1,904
Large GWAS
African American or Afro-Caribbean
Hodonsky CJ et al. “Genome-wide association study of red blood cell traits in Hispanics/Latinos: The Hispanic Community Health Study/Study of Latinos.” Plos Genetics 13(4):e1006760 (2017)
Allele T
OR 0.55
p 3.0e-12
N 12,502
Large GWAS
Hispanic or Latin American
About FAM234A
Located in cell surface. [provided by Alliance of Genome Resources, Jul 2025]
View all FAM234A variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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