rs994280

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GWAS Catalog Trait Associations (3)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

bipolar disorder, Crohn's disease

Wang BR et al. “Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.” Journal of Affective Disorders 348:167-174 (2024)

Allele A

OR 0.01

p 1.0e-8

N 453,732

Large GWAS

European

bipolar disorder

Bigdeli TB et al. “Genome-Wide Association Studies of Schizophrenia and Bipolar Disorder in a Diverse Cohort of US Veterans.” Schizophrenia Bulletin 47(2):517-529 (2021)

Allele A

OR 1.07

p 3.0e-8

N 119,005

Large GWAS

multi-ancestry

bipolar disorder, inflammatory bowel disease

Wang BR et al. “Genetic correlation, shared loci, but no causality between bipolar disorder and inflammatory bowel disease: A genome-wide pleiotropic analysis.” Journal of Affective Disorders 348:167-174 (2024)

Allele A

OR 0.01

p 4.0e-8

N 473,423

Large GWAS

European

This variant is in our database but has no known associations or PRS memberships yet.

Gene information from NCBI Gene. Variant classifications from ClinVar.

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