Trait
SNPs associated with Congenital heart disease
6 genetic variants across 4 genes have been associated with Congenital heart disease in published research. Key genes include MTHFR, MTRR, SLC44A2.
Associated variants6 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1802059 | MTRR | Increased risk of congenital heart disease | Meta-analysis |
| rs870142 | STX18-AS1 | GWAS association (p=3.0e-10) | Large GWAS |
| rs2360743 | SLC44A2 | GWAS association (p=7.0e-13) | Small GWAS |
| rs55877192 | — | GWAS association (p=1.0e-09) | Small GWAS |
| rs10380 | MTRR | Increased congenital heart disease risk | Preliminary work |
| rs2066470 | MTHFR | Increased congenital heart disease risk in offspring | Preliminary work |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.