Trait

SNPs associated with Down syndrome

2 genetic variants across 1 genes have been associated with Down syndrome in published research. Key genes include MTRR.

Associated variants2 total

rsidGeneEffectEvidence
rs1801394MTRRIncreased maternal risk of Down syndrome offspringMeta-analysis
rs1802059MTRRIncreased maternal risk for Down syndrome offspringMeta-analysis

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Down syndrome — SNPs & genetic associations — Gene Wizard