Trait

SNPs associated with Intervertebral disc degeneration

2 genetic variants across 2 genes have been associated with Intervertebral disc degeneration in published research. Key genes include COL1A1, GDF5.

Associated variants2 total

rsidGeneEffectEvidence
rs143383GDF5Increased susceptibility to lumbar disc degenerationMeta-analysis
rs1800012COL1A1Increased risk of disc degenerationMeta-analysis

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Intervertebral disc degeneration — SNPs & genetic associations — Gene Wizard