Trait

SNPs associated with Knee osteoarthritis

3 genetic variants across 3 genes have been associated with Knee osteoarthritis in published research. Key genes include ACE, ESR1, HLA-DQB1.

Associated variants3 total

rsidGeneEffectEvidence
rs2234693ESR1Increased risk of knee osteoarthritisMeta-analysis
rs7775228HLA-DQB1Increased knee osteoarthritis risk in East Asian populationsLarge GWAS
rs4343ACEIncreased knee osteoarthritis riskCandidate gene study

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

Knee osteoarthritis — SNPs & genetic associations — Gene Wizard