Trait
SNPs associated with LDL cholesterol
8 genetic variants across 7 genes have been associated with LDL cholesterol in published research. Key genes include APOB, APOE, CETP.
Associated variants8 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs1799883 | FABP2 | Elevated LDL cholesterol levels | Meta-analysis |
| rs5882 | CETP | Elevated LDL cholesterol | Major Consortium Study |
| rs4988235 | MCM6 | Lower LDL cholesterol levels | Large GWAS |
| rs429358 | APOE | Elevated LDL cholesterol levels | Small GWAS |
| rs5742904 | APOB | Elevated LDL cholesterol levels | Small GWAS |
| rs2075650 | TOMM40 | Elevated LDL cholesterol levels | Candidate gene study |
| rs4253778 | PPARA | Elevated LDL cholesterol levels | Candidate gene study |
| rs7412 | APOE | Decreased LDL cholesterol levels | Preliminary work |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.