Trait
SNPs associated with LDL cholesterol change measurement
7 genetic variants across 7 genes have been associated with LDL cholesterol change measurement in published research. Key genes include APOB, APOC1, APOE.
Associated variants7 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs151193009 | PCSK9 | GWAS association (p=8.0e-32) | Large GWAS |
| rs629301 | CELSR2 | GWAS association (p=2.0e-17) | Large GWAS |
| rs7412 | APOE | GWAS association (p=7.0e-15) | Large GWAS |
| rs445925 | APOC1 | GWAS association (p=1.0e-13) | Large GWAS |
| rs13306194 | APOB | GWAS association (p=1.0e-12) | Large GWAS |
| rs200990725 | LDLR | GWAS association (p=3.0e-08) | Large GWAS |
| rs7185272 | PKD1L3 | GWAS association (p=5.0e-08) | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.