Trait
SNPs associated with Myeloproliferative Neoplasm Susceptibility
6 genetic variants across 2 genes have been associated with Myeloproliferative Neoplasm Susceptibility in published research. Key genes include JAK2, TERT.
Associated variants6 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2736100 | TERT | Higher myeloproliferative neoplasm risk | Meta-analysis |
| rs12343867 | JAK2 | JAK2 46/1 haplotype increases MPN risk ~3-fold | Large GWAS |
| rs12340895 | JAK2 | JAK2 46/1 haplotype increases MPN risk ~3.7-fold | Large GWAS |
| rs4495487 | JAK2 | JAK2 46/1 haplotype tag SNP for MPN risk | Large GWAS |
| rs10974944 | JAK2 | JAK2 46/1 haplotype increases MPN risk ~3-fold | Large GWAS |
| rs3780374 | JAK2 | JAK2 46/1 haplotype tag SNP for MPN risk | Large GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.