Trait

SNPs associated with Systemic sclerosis

3 genetic variants across 2 genes have been associated with Systemic sclerosis in published research. Key genes include HLA-DQB1, IRF5.

Associated variants3 total

rsid	Gene	Effect	Evidence
rs2004640	IRF5	Increased risk of systemic sclerosis	Meta-analysis
rs6457617	HLA-DQB1	Higher risk of systemic sclerosis	Large GWAS
rs10488631	IRF5	Higher risk of systemic sclerosis	Large GWAS

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.