ACAP2
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
Summary
Enables GTPase activator activity. Acts upstream of or within actin filament-based process. Located in ruffle. [provided by Alliance of Genome Resources, Apr 2025]
Known Variants20 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs373402885 | 3:195,000,106 | T/C | — | uncertain significance |
| rs371113193 | 3:195,000,130 | C/T | — | uncertain significance |
| rs182784214 | 3:195,001,126 | G/A | downstream gene variant | — |
| rs143018690 | 3:195,012,451 | C/T | — | uncertain significance |
| rs777709903 | 3:195,012,525 | T/C | — | uncertain significance |
| rs2474769345 | 3:195,013,160 | G/A | — | uncertain significance |
| rs779657743 | 3:195,013,163 | G/A | — | uncertain significance |
| rs139056381 | 3:195,015,477 | G/A | — | uncertain significance |
| rs1161438810 | 3:195,018,006 | A/G | — | uncertain significance |
| rs566100558 | 3:195,022,700 | A/C | — | uncertain significance |
| rs777687187 | 3:195,041,485 | C/T | — | uncertain significance |
| rs1020264470 | 3:195,041,501 | A/C | — | uncertain significance |
| rs1232089082 | 3:195,047,681 | C/T | — | uncertain significance |
| rs1362742677 | 3:195,063,207 | A/C | — | uncertain significance |
| rs1245396911 | 3:195,063,228 | C/T | — | uncertain significance |
| rs571571326 | 3:195,101,649 | C/A | — | — |
| rs2474172928 | 3:195,102,633 | T/A | — | uncertain significance |
| rs113782604 | 3:195,112,849 | A/G | — | likely benign |
| rs112341402 | 3:195,148,915 | T/C | — | — |
| rs1426008854 | 3:195,163,564 | C/G | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.