rs182784214

This is a downstream gene variant variant in the ACAP2 gene.

GWAS Catalog Trait Associations (1)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

bone fracture

Verma A et al. Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program. Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele G
OR 3.46
p 1.0e-12
N 570,089
Major Consortium StudyLarge GWAS
multi-ancestry

About ACAP2

Enables GTPase activator activity. Acts upstream of or within actin filament-based process. Located in ruffle. [provided by Alliance of Genome Resources, Apr 2025]

View all ACAP2 variants →

Gene information from NCBI Gene. Variant classifications from ClinVar.

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