ADCY2
adenylate cyclase 2
Summary
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008]
Known Variants53 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs758658597 | 5:7,396,489 | C/G | — | uncertain significance |
| rs2477788656 | 5:7,396,524 | T/C | — | uncertain significance |
| rs2477788716 | 5:7,396,531 | G/C | — | uncertain significance |
| rs2477788812 | 5:7,396,545 | C/T | — | uncertain significance |
| rs1457078080 | 5:7,396,599 | G/T | — | uncertain significance |
| rs74730018 | 5:7,413,864 | C/G | intron variant | — |
| rs78765360 | 5:7,418,682 | C/T | intron variant | — |
| rs530573459 | 5:7,465,441 | C/T | — | — |
| rs10038196 | 5:7,517,418 | T/G | intron variant | — |
| rs17826816 | 5:7,519,298 | A/G | intron variant | — |
| rs13166360 | 5:7,520,881 | G/T | missense variant | — |
| rs386352276 | 5:7,520,931 | C/G | — | uncertain significance |
| rs4702473 | 5:7,528,558 | T/A | — | — |
| rs6880956 | 5:7,530,324 | A/G | regulatory region variant | — |
| rs1846681 | 5:7,530,741 | A/T | — | — |
| rs13174252 | 5:7,530,931 | A/G | intron variant | — |
| rs529044014 | 5:7,544,774 | A/G | — | — |
| rs1946468 | 5:7,617,232 | A/C | — | — |
| rs4702484 | 5:7,649,860 | C/G | — | — |
| rs2914295 | 5:7,652,834 | C/T | intron variant | — |
| rs184421129 | 5:7,657,396 | G/A | intron variant | — |
| rs2477851312 | 5:7,698,403 | A/G | — | uncertain significance |
| rs12515674 | 5:7,702,309 | A/T | intron variant | — |
| rs2477885408 | 5:7,707,883 | G/T | — | uncertain significance |
| rs200097682 | 5:7,709,352 | T/A | — | uncertain significance |
| rs1300093452 | 5:7,709,411 | T/A | — | uncertain significance |
| rs2477891049 | 5:7,709,424 | G/C | — | uncertain significance |
| rs1742513524 | 5:7,743,810 | C/T | — | uncertain significance |
| rs202064623 | 5:7,743,842 | G/A | — | uncertain significance |
| rs1421041093 | 5:7,757,593 | T/C | — | uncertain significance |
| rs201928490 | 5:7,757,641 | G/A | — | uncertain significance |
| rs2126458435 | 5:7,757,666 | A/G | — | likely benign |
| rs2478063934 | 5:7,757,682 | A/C | — | uncertain significance |
| rs1560953572 | 5:7,757,686 | C/G | — | uncertain significance |
| rs1560953625 | 5:7,757,689 | T/C | — | uncertain significance |
| rs2478064172 | 5:7,757,692 | T/C | — | uncertain significance |
| rs1431640036 | 5:7,757,694 | A/G | — | uncertain significance |
| rs1312383172 | 5:7,757,695 | A/G | — | uncertain significance |
| rs4072341 | 5:7,757,705 | T/C | — | benign |
| rs4479814 | 5:7,757,715 | C/T | — | benign |
| rs1455285873 | 5:7,773,054 | T/C | — | uncertain significance |
| rs1743601709 | 5:7,773,129 | A/T | — | uncertain significance |
| rs1229200083 | 5:7,789,810 | G/A | — | uncertain significance |
| rs2290910 | 5:7,802,363 | C/T | — | benign |
| rs140943409 | 5:7,802,468 | C/T | — | likely benign |
| rs148142196 | 5:7,804,706 | C/G | — | benign |
| rs760829715 | 5:7,804,803 | C/A | — | uncertain significance |
| rs326155 | 5:7,816,645 | A/G | regulatory region variant | — |
| rs148980899 | 5:7,816,997 | A/G | — | uncertain significance |
| rs2478302499 | 5:7,820,738 | T/C | — | uncertain significance |
| rs926516464 | 5:7,820,782 | G/A | — | uncertain significance |
| rs2478321671 | 5:7,826,946 | A/G | — | uncertain significance |
| rs200555888 | 5:7,826,973 | G/A | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.