Trait
SNPs associated with Cognitive function
738 genetic variants across 158 genes have been associated with Cognitive function in published research. Key genes include ACSL5, ADCY2, APOE.
Associated variants738 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs429358 | APOE | GWAS association (p=2.0e-08) | Meta-analysis |
| rs45543740 | — | GWAS association (p=2.0e-08) | Major Consortium Study |
| rs4805491 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs140830767 | — | GWAS association (p=4.0e-08) | Major Consortium Study |
| rs7623659 | RHOA | GWAS association (p=4.0e-57) | Large GWAS |
| rs9401593 | — | GWAS association (p=5.0e-55) | Large GWAS |
| rs72793812 | ATXN2L | GWAS association (p=8.0e-35) | Large GWAS |
| rs11123820 | — | GWAS association (p=1.0e-32) | Large GWAS |
| rs17304079 | — | GWAS association (p=1.0e-32) | Large GWAS |
| rs3128341 | — | GWAS association (p=4.0e-30) | Large GWAS |
| rs1343775 | — | GWAS association (p=1.0e-29) | Large GWAS |
| rs2352974 | TRAIP | GWAS association (p=5.0e-29) | Large GWAS |
| rs254781 | MEF2C-AS2 | GWAS association (p=1.0e-28) | Large GWAS |
| rs11191193 | — | GWAS association (p=2.0e-28) | Large GWAS |
| rs10189857 | — | GWAS association (p=1.0e-27) | Large GWAS |
| rs1906252 | — | GWAS association (p=4.0e-27) | Large GWAS |
| rs12128707 | — | GWAS association (p=5.0e-27) | Large GWAS |
| rs4500960 | — | GWAS association (p=7.0e-26) | Large GWAS |
| rs34244947 | — | GWAS association (p=4.0e-25) | Large GWAS |
| rs2726513 | — | GWAS association (p=4.0e-25) | Large GWAS |
| rs11678980 | — | GWAS association (p=6.0e-25) | Large GWAS |
| rs11662271 | DCC | GWAS association (p=3.0e-24) | Large GWAS |
| rs2819336 | — | GWAS association (p=3.0e-22) | Large GWAS |
| rs1054442 | — | GWAS association (p=7.0e-22) | Large GWAS |
| rs6666119 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs57352738 | — | GWAS association (p=4.0e-21) | Large GWAS |
| rs1455349 | — | GWAS association (p=2.0e-20) | Large GWAS |
| rs4913077 | CYSTM1 | GWAS association (p=5.0e-20) | Large GWAS |
| rs148696809 | — | GWAS association (p=8.0e-20) | Large GWAS |
| rs10874938 | LOC101928219 | GWAS association (p=1.0e-19) | Large GWAS |
| rs4395728 | — | GWAS association (p=2.0e-19) | Large GWAS |
| rs2073526 | — | GWAS association (p=3.0e-19) | Large GWAS |
| rs7325960 | — | GWAS association (p=4.0e-19) | Large GWAS |
| rs12448902 | SH2B1 | GWAS association (p=5.0e-19) | Large GWAS |
| rs13428598 | ARHGAP15 | GWAS association (p=1.0e-18) | Large GWAS |
| rs750472 | FOXH1 | GWAS association (p=1.0e-18) | Large GWAS |
| rs34811474 | — | GWAS association (p=2.0e-18) | Large GWAS |
| rs3747631 | LRRN2 | GWAS association (p=3.0e-18) | Large GWAS |
| rs335426 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs3740422 | OGA | GWAS association (p=1.0e-17) | Large GWAS |
| rs13217795 | FOXO3 | Lower reaction time (faster cognitive processing) | Large GWAS |
| rs4700393 | — | GWAS association (p=2.0e-17) | Large GWAS |
| rs7633520 | RPL15 | GWAS association (p=3.0e-17) | Large GWAS |
| rs1969355 | MTRFR | GWAS association (p=4.0e-17) | Large GWAS |
| rs13262595 | TSNARE1 | GWAS association (p=8.0e-17) | Large GWAS |
| rs3860537 | — | GWAS association (p=1.0e-16) | Large GWAS |
| rs17669337 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs12601380 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs9328534 | — | GWAS association (p=2.0e-16) | Large GWAS |
| rs10922907 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs1892419 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs10875914 | KMT2D | GWAS association (p=3.0e-16) | Large GWAS |
| rs2743461 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs2725371 | — | GWAS association (p=3.0e-16) | Large GWAS |
| rs6550835 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs7867618 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs112780312 | GATAD2B | GWAS association (p=5.0e-16) | Large GWAS |
| rs13163336 | LINC00461 | GWAS association (p=5.0e-16) | Large GWAS |
| rs11720523 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs34389480 | — | GWAS association (p=8.0e-16) | Large GWAS |
| rs4325706 | LINC01958 | GWAS association (p=1.0e-15) | Large GWAS |
| rs7038525 | — | GWAS association (p=1.0e-15) | Large GWAS |
| rs4669634 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs1375561 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs2114033 | — | GWAS association (p=2.0e-15) | Large GWAS |
| rs1255223 | CEP57 | GWAS association (p=2.0e-15) | Large GWAS |
| rs34795510 | — | GWAS association (p=3.0e-15) | Large GWAS |
| rs76160968 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs6535809 | GATB | GWAS association (p=5.0e-15) | Large GWAS |
| rs2252003 | — | GWAS association (p=5.0e-15) | Large GWAS |
| rs4314918 | ST3GAL3 | GWAS association (p=8.0e-15) | Large GWAS |
| rs1831539 | — | GWAS association (p=9.0e-15) | Large GWAS |
| rs5751191 | — | GWAS association (p=9.0e-15) | Large GWAS |
| rs10750866 | — | GWAS association (p=9.0e-15) | Large GWAS |
| rs17048855 | — | GWAS association (p=1.0e-14) | Large GWAS |
| rs7556896 | ERBB4 | GWAS association (p=2.0e-14) | Large GWAS |
| rs7937910 | — | GWAS association (p=2.0e-14) | Large GWAS |
| rs75654367 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs75973558 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs75751670 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs4463213 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs7299037 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs12325429 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs4131987 | — | GWAS association (p=3.0e-14) | Large GWAS |
| rs383618 | LOC101927078 | GWAS association (p=4.0e-14) | Large GWAS |
| rs17443541 | — | GWAS association (p=4.0e-14) | Large GWAS |
| rs6975134 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs6581157 | LOC283387 | GWAS association (p=5.0e-14) | Large GWAS |
| rs73581580 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs3896224 | — | GWAS association (p=5.0e-14) | Large GWAS |
| rs975303 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs178203 | — | GWAS association (p=6.0e-14) | Large GWAS |
| rs9655780 | — | GWAS association (p=9.0e-14) | Large GWAS |
| rs77999825 | — | GWAS association (p=9.0e-14) | Large GWAS |
| rs34216058 | TTC29 | GWAS association (p=1.0e-13) | Large GWAS |
| rs1567154 | — | GWAS association (p=1.0e-13) | Large GWAS |
| rs77483376 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs12761761 | PPP2R2D | GWAS association (p=2.0e-13) | Large GWAS |
| rs4863516 | — | GWAS association (p=2.0e-13) | Large GWAS |
| rs1812587 | — | GWAS association (p=2.0e-13) | Large GWAS |
Showing the top 100 of 738 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.