rs73581580
▶GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (7)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
mathematical ability
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.02
p 7.0e-21
N 811,539
Large GWAS
European
cognitive function measurement
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.03
p 5.0e-14
N 402,382
Large GWAS
European
suicidal ideation, suicide behaviour
Kimbrel NA et al. “Identification of Novel, Replicable Genetic Risk Loci for Suicidal Thoughts and Behaviors Among US Military Veterans.” Jama Psychiatry 80(2):135-145 (2023)
Allele A
OR —
p 4.0e-11
N 452,767
Large GWAS
European
suicidal ideation
Ashley-Koch AE et al. “Genome-wide association study identifies four pan-ancestry loci for suicidal ideation in the Million Veteran Program.” Plos Genetics 19(3):e1010623 (2023)
Allele A
OR 1.07
p 1.0e-10
N 438,849
Major Consortium StudyLarge GWAS
European
physical activity measurement
Wang Z et al. “Genome-wide association analyses of physical activity and sedentary behavior provide insights into underlying mechanisms and roles in disease prevention.” Nature Genetics 54(9):1332-1344 (2022)
Allele G
OR 0.04
p 2.0e-10
N 526,725
Large GWAS
European
chronic musculoskeletal pain
Tsepilov YA et al. “Analysis of genetically independent phenotypes identifies shared genetic factors associated with chronic musculoskeletal pain conditions.” Communications Biology 3(1):329 (2020)
Allele A
OR 0.02
p 4.0e-9
N 265,000
Large GWAS
multi-ancestry
self reported educational attainment
Lee JJ et al. “Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals.” Nature Genetics 50(8):1112-1121 (2018)
Allele A
OR 0.02
p 6.0e-16
N 1,131,881
Large GWAS
European
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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