ADSS2
adenylosuccinate synthase 2
Summary
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
Known Variants22 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs2528067497 | 1:244,574,678 | G/A | — | uncertain significance |
| rs1459257754 | 1:244,574,680 | G/T | — | uncertain significance |
| rs768756706 | 1:244,574,716 | T/G | — | uncertain significance |
| rs3102460 | 1:244,576,717 | C/T | upstream gene variant | — |
| rs2528077622 | 1:244,579,324 | A/C | — | uncertain significance |
| rs147946123 | 1:244,579,342 | G/A | — | uncertain significance |
| rs778015979 | 1:244,580,955 | C/T | — | uncertain significance |
| rs201194182 | 1:244,582,097 | C/T | — | uncertain significance |
| rs781125289 | 1:244,582,154 | T/C | — | uncertain significance |
| rs771643025 | 1:244,583,555 | T/A | — | uncertain significance |
| rs1321397058 | 1:244,583,582 | A/C | — | uncertain significance |
| rs1361108729 | 1:244,587,650 | T/C | — | uncertain significance |
| rs375507039 | 1:244,595,918 | T/C | intron variant | — |
| rs754059837 | 1:244,600,979 | G/A | — | uncertain significance |
| rs142102289 | 1:244,600,984 | A/T | — | uncertain significance |
| rs139290156 | 1:244,601,020 | A/C | — | uncertain significance |
| rs1347271453 | 1:244,614,961 | G/T | — | uncertain significance |
| rs902288957 | 1:244,614,975 | G/C | — | uncertain significance |
| rs200767219 | 1:244,615,071 | C/T | — | uncertain significance |
| rs906629171 | 1:244,615,074 | C/A | — | uncertain significance |
| rs765386619 | 1:244,615,101 | A/C | — | uncertain significance |
| rs1161934794 | 1:244,615,107 | C/T | — | likely benign |
Gene information from NCBI Gene. Variant classifications from ClinVar.