rs375507039
This is a intron variant variant in the ADSS2 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
intraocular pressure measurement
Gao XR et al. “Whole-exome sequencing study identifies rare variants and genes associated with intraocular pressure and glaucoma.” Nature Communications 13(1):7376 (2022)
Allele C
OR 7.69
p 5.0e-9
N 110,260
Large GWAS
multi-ancestry
About ADSS2
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
View all ADSS2 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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