AJAP1
adherens junctions associated protein 1
Summary
Enables beta-catenin binding activity. Involved in negative regulation of cell-matrix adhesion; negative regulation of wound healing; and regulation of polarized epithelial cell differentiation. Located in several cellular components, including adherens junction; basolateral plasma membrane; and cell-cell contact zone. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants29 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs373570588 | 1:4,771,950 | C/T | — | likely benign |
| rs149284997 | 1:4,772,034 | C/T | — | benign |
| rs762904463 | 1:4,772,093 | C/T | — | uncertain significance |
| rs759795088 | 1:4,772,181 | C/T | — | uncertain significance |
| rs765357051 | 1:4,772,184 | G/T | — | uncertain significance |
| rs780806292 | 1:4,772,223 | C/T | — | uncertain significance |
| rs145803857 | 1:4,772,297 | G/A | — | uncertain significance |
| rs754823601 | 1:4,772,328 | C/T | — | uncertain significance |
| rs775807539 | 1:4,772,355 | C/T | — | uncertain significance |
| rs774900566 | 1:4,772,378 | G/A | — | uncertain significance |
| rs550924407 | 1:4,772,388 | G/T | — | uncertain significance |
| rs2523478757 | 1:4,772,428 | C/G | — | uncertain significance |
| rs1340787438 | 1:4,772,446 | C/G | — | uncertain significance |
| rs764876909 | 1:4,772,498 | G/A | — | uncertain significance |
| rs751341447 | 1:4,772,513 | A/G | — | uncertain significance |
| rs76065876 | 1:4,772,535 | G/A | — | benign |
| rs148805869 | 1:4,772,564 | C/T | — | uncertain significance |
| rs376309978 | 1:4,772,567 | A/G | — | uncertain significance |
| rs1028464681 | 1:4,772,613 | C/G | — | uncertain significance |
| rs1200789156 | 1:4,772,708 | A/G | — | uncertain significance |
| rs2523480328 | 1:4,772,722 | A/T | — | uncertain significance |
| rs764195645 | 1:4,772,754 | C/T | — | uncertain significance |
| rs761790946 | 1:4,829,931 | T/A | — | uncertain significance |
| rs267598631 | 1:4,832,363 | G/A | — | uncertain significance |
| rs781175711 | 1:4,832,546 | C/T | — | uncertain significance |
| rs368367088 | 1:4,832,548 | A/T | — | uncertain significance |
| rs1263891334 | 1:4,832,554 | G/T | — | uncertain significance |
| rs530270410 | 1:4,834,504 | G/A | — | uncertain significance |
| rs909757 | 1:4,850,823 | T/C | 3 prime UTR variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.