ALPG

alkaline phosphatase, germ cell

Summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The product of this gene is a membrane bound glycosylated enzyme, localized to testis, thymus and certain germ cell tumors, that is closely related to both the placental and intestinal forms of alkaline phosphatase. [provided by RefSeq, Jul 2008]

Known Variants64 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs556454293	2:233,271,626	C/T	—	uncertain significance
rs61730279	2:233,271,628	C/T	—	benign
rs117962550	2:233,271,731	C/A	intron variant	—
rs375292491	2:233,271,796	C/T	—	uncertain significance
rs776010626	2:233,271,797	G/A	—	uncertain significance
rs761500611	2:233,271,807	C/T	—	likely benign
rs2469543723	2:233,271,809	A/C	—	uncertain significance
rs562795167	2:233,271,823	G/A	—	uncertain significance
rs1230742683	2:233,271,848	C/G	—	uncertain significance
rs61730280	2:233,271,852	C/T	—	benign
rs568507509	2:233,271,853	G/A	—	uncertain significance
rs147837468	2:233,271,868	A/G	—	uncertain significance
rs146482704	2:233,272,091	C/T	—	benign
rs112965314	2:233,272,095	A/T	—	benign
rs370614317	2:233,272,363	C/G	—	uncertain significance
rs149658741	2:233,272,364	G/A	—	uncertain significance
rs201503000	2:233,272,406	G/A	—	uncertain significance
rs764875560	2:233,272,409	C/T	—	uncertain significance
rs139491713	2:233,272,410	G/T	—	uncertain significance
rs147653632	2:233,272,453	C/T	—	benign
rs372574780	2:233,272,454	G/A	—	uncertain significance
rs1345686481	2:233,272,559	G/C	—	uncertain significance
rs747056715	2:233,272,584	C/T	—	uncertain significance
rs113898433	2:233,272,595	T/C	—	likely benign
rs2469545340	2:233,272,603	C/T	—	uncertain significance
rs529459697	2:233,272,611	G/A	—	likely benign
rs146780985	2:233,272,616	C/T	—	benign
rs145892470	2:233,272,617	G/A	—	uncertain significance
rs749719597	2:233,272,632	C/T	—	uncertain significance
rs771594260	2:233,272,645	C/T	—	uncertain significance
rs199598336	2:233,272,656	G/A	—	likely benign
rs769658713	2:233,272,695	G/A	—	uncertain significance
rs368869875	2:233,272,699	C/T	—	uncertain significance
rs75920311	2:233,273,011	C/G	—	benign
rs75080031	2:233,273,018	G/A	—	benign
rs141105098	2:233,273,022	C/T	—	uncertain significance
rs1697133522	2:233,273,226	T/C	—	uncertain significance
rs1412068149	2:233,273,272	C/A	—	uncertain significance
rs2469547144	2:233,273,513	G/A	—	uncertain significance
rs1450658250	2:233,273,718	C/T	—	uncertain significance
rs1345305890	2:233,273,756	G/A	—	uncertain significance
rs1389211324	2:233,273,777	G/A	—	uncertain significance
rs1269982165	2:233,273,808	G/A	—	uncertain significance
rs1209999184	2:233,273,821	C/G	—	uncertain significance
rs567230735	2:233,273,902	A/G	—	—
rs544925049	2:233,274,074	G/A	—	uncertain significance
rs1374311427	2:233,274,092	T/G	—	uncertain significance
rs748973186	2:233,274,119	A/G	—	uncertain significance
rs1339270909	2:233,274,124	C/G	—	uncertain significance
rs746873216	2:233,274,132	G/C	—	uncertain significance
rs2090543	2:233,274,145	G/C	synonymous variant	—
rs528210448	2:233,274,146	G/A	—	uncertain significance
rs536903121	2:233,274,168	G/A	—	likely benign
rs2469548465	2:233,274,379	C/T	—	uncertain significance
rs756069446	2:233,274,381	C/T	—	likely benign
rs1430704872	2:233,274,391	G/A	—	uncertain significance
rs373170842	2:233,274,395	T/A	—	uncertain significance
rs2469548576	2:233,274,460	T/C	—	uncertain significance
rs754742852	2:233,274,466	C/G	—	uncertain significance
rs1243822743	2:233,274,473	C/T	—	uncertain significance
rs61730278	2:233,274,476	G/C	—	benign
rs201615790	2:233,274,482	G/A	—	likely benign
rs781457495	2:233,274,508	C/G	—	uncertain significance
rs575876557	2:233,274,779	T/C	—	—

Gene information from NCBI Gene. Variant classifications from ClinVar.