ALPK3

alpha kinase 3

Summary

Predicted to enable ATP binding activity; protein serine kinase activity; and protein serine/threonine kinase activity. Predicted to be involved in cardiac muscle cell development. Predicted to be active in nucleus. Implicated in hypertrophic cardiomyopathy 27. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants1,934 total

rsidPosition (GRCh37)AllelesClassClinVar
rs5573601715:85,360,004C/A—benign
rs37067914615:85,360,048G/T—likely benign
rs138728462415:85,360,075C/T—uncertain significance
rs135155107915:85,360,077A/T—uncertain significance
rs250568781615:85,360,081G/A—uncertain significance
rs2840884015:85,360,086G/A—likely benign
rs250568784115:85,360,089T/A—likely benign
rs117357258615:85,360,092G/T—uncertain significance
rs128611998315:85,360,098C/T—likely benign
rs1185735615:85,360,101C/T—benign
rs127428499915:85,360,107G/A—likely benign
rs250568788115:85,360,112A/G—uncertain significance
rs77699054315:85,360,114C/T—uncertain significance
rs250568789315:85,360,123G/A—uncertain significance
rs13887072815:85,360,125G/A—likely benign
rs75165259915:85,360,138G/C—uncertain significance
rs37377047215:85,360,148G/A—uncertain significance
rs75370971015:85,360,149G/A—likely benign
rs14600569615:85,360,152G/A—likely benign
rs132285328415:85,360,153G/A—uncertain significance
rs13958347415:85,360,156C/T—uncertain significance
rs134950520115:85,360,157C/T—uncertain significance
rs196336294215:85,360,168C/G—uncertain significance
rs250568797615:85,360,172T/A—uncertain significance
rs250568799215:85,360,179G/A—uncertain significance
rs75915362615:85,360,180C/T—uncertain significance
rs14932021515:85,360,182C/T—likely benign
rs77590977415:85,360,184C/T—likely benign
rs250568800515:85,360,187G/A—uncertain significance
rs124981833515:85,360,189C/A—uncertain significance
rs127921608515:85,360,192C/G—uncertain significance
rs118900159515:85,360,193C/T—uncertain significance
rs53275617315:85,360,195C/A—likely benign
rs147187805615:85,360,196G/A—uncertain significance
rs116252980415:85,360,197G/T—likely benign
rs250568803215:85,360,200T/C—likely benign
rs76459397015:85,360,203C/G—uncertain significance
rs133417104815:85,360,205C/A—uncertain significance
rs250568805215:85,360,207A/T—uncertain significance
rs147066012815:85,360,213C/G—uncertain significance
rs136978673615:85,360,217C/A—uncertain significance
rs141501610315:85,360,218G/A—likely benign
rs133582713215:85,360,220T/C—uncertain significance
rs98001352115:85,360,221T/A—likely benign
rs196336433815:85,360,222G/A—uncertain significance
rs37162884415:85,360,223A/T—uncertain significance
rs75071603115:85,360,228G/C—uncertain significance
rs37385351015:85,360,231C/T—conflicting classifications of pathogenicity
rs196336461115:85,360,234C/G—uncertain significance
rs196336472315:85,360,239C/T—likely benign
rs75827583615:85,360,241C/T—uncertain significance
rs2841629515:85,360,242G/T—likely benign
rs52881101915:85,360,248G/A—likely benign
rs105752368215:85,360,250C/T—uncertain significance
rs11538925315:85,360,252C/T—uncertain significance
rs75679700115:85,360,253G/T—conflicting classifications of pathogenicity
rs78065461715:85,360,254T/C—likely benign
rs76943114815:85,360,260C/A—likely benign
rs77572019915:85,360,261C/T—uncertain significance
rs250568817415:85,360,263C/T—likely benign
rs2843135415:85,360,271G/A—uncertain significance
rs77488302815:85,360,274C/G—uncertain significance
rs37679866715:85,360,275G/A—likely benign
rs76775465615:85,360,276G/C—uncertain significance
rs127675926015:85,360,282G/A—uncertain significance
rs77341649815:85,360,284G/A—likely benign
rs100110263815:85,360,285C/A—uncertain significance
rs76655931915:85,360,295G/A—uncertain significance
rs156708474315:85,360,297G/A—conflicting classifications of pathogenicity
rs14981826615:85,360,300C/T—uncertain significance
rs75817009515:85,360,303G/C—uncertain significance
rs134742224015:85,360,306C/T—uncertain significance
rs76376341115:85,360,307C/T—uncertain significance
rs214154168915:85,360,313G/C—uncertain significance
rs88769583115:85,360,314C/A—uncertain significance
rs196336630915:85,360,320G/T—likely benign
rs101520466815:85,360,327C/T—uncertain significance
rs36986055715:85,360,334T/G—uncertain significance
rs214154171815:85,360,339G/A—uncertain significance
rs214154172115:85,360,340A/T—uncertain significance
rs74530960515:85,360,343A/G—uncertain significance
rs196336673815:85,360,350C/T—likely benign
rs122668514315:85,360,351C/A—uncertain significance
rs77970683015:85,360,352G/T—uncertain significance
rs214154175715:85,360,363C/T—uncertain significance
rs102829544015:85,360,364T/C—uncertain significance
rs86788747815:85,360,367C/G—uncertain significance
rs98707384115:85,360,368G/A—likely benign
rs99468164515:85,360,369A/C—likely benign
rs129933061915:85,360,370G/A—uncertain significance
rs76910663215:85,360,371G/A—likely benign
rs102976318015:85,360,372C/T—uncertain significance
rs130527565515:85,360,375C/A—uncertain significance
rs147128370415:85,360,377C/G—likely benign
rs86837526115:85,360,378G/A—conflicting classifications of pathogenicity
rs77483487015:85,360,379G/A—uncertain significance
rs250568844915:85,360,388A/G—uncertain significance
rs128072877515:85,360,391C/T—uncertain significance
rs100685662215:85,360,394G/A—uncertain significance
rs250568846815:85,360,401C/T—likely benign

Showing 100 of 1,934 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.