Trait
SNPs associated with QT interval
421 genetic variants across 107 genes have been associated with QT interval in published research. Key genes include ALPK3, ARID2, ARIH2.
Associated variants421 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12143842 | — | GWAS association (p=1.0e-83) | Meta-analysis |
| rs2074238 | KCNQ1 | GWAS association (p=3.0e-17) | Meta-analysis |
| rs11153730 | — | GWAS association (p=2.0e-29) | Meta-analysis |
| rs1805128 | KCNE1 | GWAS association (p=2.0e-143) | Meta-analysis |
| rs2010491 | — | GWAS association (p=2.0e-89) | Meta-analysis |
| rs2074518 | LIG3 | GWAS association (p=6.0e-12) | Meta-analysis |
| rs950843 | — | GWAS association (p=1.0e-20) | Meta-analysis |
| rs12668582 | KCNH2 | GWAS association (p=5.0e-18) | Meta-analysis |
| rs12035622 | — | GWAS association (p=9.0e-18) | Meta-analysis |
| rs11121483 | — | GWAS association (p=5.0e-12) | Meta-analysis |
| rs11643990 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs4793397 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs174546 | FADS1 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs28637922 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs4485352 | CNOT1 | GWAS association (p=3.0e-225) | Large GWAS |
| rs846111 | RNF207 | GWAS association (p=1.0e-16) | Large GWAS |
| rs758890 | KCNH2 | GWAS association (p=6.0e-173) | Large GWAS |
| rs7191330 | — | GWAS association (p=1.0e-141) | Large GWAS |
| rs1591734 | — | GWAS association (p=2.0e-135) | Large GWAS |
| rs3934467 | — | GWAS association (p=3.0e-129) | Large GWAS |
| rs12941598 | LOC124904100 | GWAS association (p=9.0e-84) | Large GWAS |
| rs7373492 | SCN5A | GWAS association (p=2.0e-80) | Large GWAS |
| rs7188697 | CNOT1 | GWAS association (p=7.0e-25) | Large GWAS |
| rs16857031 | NOS1AP | GWAS association (p=1.0e-34) | Large GWAS |
| rs9890911 | — | GWAS association (p=1.0e-58) | Large GWAS |
| rs246196 | CNOT1 | GWAS association (p=2.0e-57) | Large GWAS |
| rs1052536 | LIG3 | GWAS association (p=4.0e-56) | Large GWAS |
| rs116015634 | — | GWAS association (p=2.0e-55) | Large GWAS |
| rs7122937 | KCNQ1 | GWAS association (p=1.0e-54) | Large GWAS |
| rs12448482 | — | GWAS association (p=2.0e-54) | Large GWAS |
| rs12315174 | — | GWAS association (p=3.0e-54) | Large GWAS |
| rs10490255 | — | GWAS association (p=1.0e-53) | Large GWAS |
| rs1805123 | KCNH2 | GWAS association (p=7.0e-51) | Large GWAS |
| rs2072413 | KCNH2 | GWAS association (p=1.0e-49) | Large GWAS |
| rs709209 | RNF207 | GWAS association (p=1.0e-48) | Large GWAS |
| rs12029454 | NOS1AP | GWAS association (p=3.0e-45) | Large GWAS |
| rs2298632 | — | GWAS association (p=4.0e-45) | Large GWAS |
| rs17061696 | KLF12 | GWAS association (p=1.0e-44) | Large GWAS |
| rs8049607 | LITAF | GWAS association (p=5.0e-15) | Large GWAS |
| rs13355516 | FAM13B | GWAS association (p=1.0e-43) | Large GWAS |
| rs9915847 | YPEL2 | GWAS association (p=3.0e-42) | Large GWAS |
| rs1706003 | — | GWAS association (p=4.0e-42) | Large GWAS |
| rs1947378 | — | GWAS association (p=1.0e-39) | Large GWAS |
| rs6669543 | — | GWAS association (p=2.0e-39) | Large GWAS |
| rs34969716 | — | GWAS association (p=2.0e-39) | Large GWAS |
| rs347272 | NOS1AP | GWAS association (p=1.0e-37) | Large GWAS |
| rs35394392 | SLC4A3 | GWAS association (p=1.0e-37) | Large GWAS |
| rs17779747 | LOC124904100 | GWAS association (p=6.0e-12) | Large GWAS |
| rs30226 | — | GWAS association (p=1.0e-36) | Large GWAS |
| rs35717017 | — | GWAS association (p=1.0e-35) | Large GWAS |
| rs1317572 | — | GWAS association (p=2.0e-34) | Large GWAS |
| rs3098202 | — | GWAS association (p=2.0e-33) | Large GWAS |
| rs3807375 | KCNH2 | GWAS association (p=3.0e-33) | Large GWAS |
| rs4657178 | NOS1AP | GWAS association (p=7.0e-33) | Large GWAS |
| rs66677602 | TTN | GWAS association (p=4.0e-32) | Large GWAS |
| rs10919070 | ATP1B1 | GWAS association (p=1.0e-31) | Large GWAS |
| rs10919071 | ATP1B1 | GWAS association (p=1.0e-15) | Large GWAS |
| rs55893552 | — | GWAS association (p=4.0e-30) | Large GWAS |
| rs74783055 | NCOA2 | GWAS association (p=1.0e-29) | Large GWAS |
| rs17774009 | — | GWAS association (p=2.0e-29) | Large GWAS |
| rs735951 | — | GWAS association (p=2.0e-28) | Large GWAS |
| rs174537 | MYRF | GWAS association (p=5.0e-28) | Large GWAS |
| rs1997571 | — | GWAS association (p=1.0e-27) | Large GWAS |
| rs56078134 | SLC12A7 | GWAS association (p=1.0e-27) | Large GWAS |
| rs10864434 | — | GWAS association (p=3.0e-27) | Large GWAS |
| rs6793245 | SCN5A | GWAS association (p=4.0e-27) | Large GWAS |
| rs185639574 | SETD6 | GWAS association (p=7.0e-27) | Large GWAS |
| rs12053903 | SCN5A | GWAS association (p=1.0e-14) | Large GWAS |
| rs72677052 | — | GWAS association (p=2.0e-26) | Large GWAS |
| rs73186030 | — | GWAS association (p=1.0e-25) | Large GWAS |
| rs1396515 | — | GWAS association (p=2.0e-25) | Large GWAS |
| rs37062 | CNOT1 | GWAS association (p=3.0e-25) | Large GWAS |
| rs661821 | — | GWAS association (p=1.0e-24) | Large GWAS |
| rs11970286 | — | GWAS association (p=2.0e-24) | Large GWAS |
| rs7737409 | — | GWAS association (p=5.0e-24) | Large GWAS |
| rs1296720 | — | GWAS association (p=2.0e-23) | Large GWAS |
| rs4951258 | NUCKS1 | GWAS association (p=3.0e-23) | Large GWAS |
| rs12210733 | — | GWAS association (p=1.0e-22) | Large GWAS |
| rs78341918 | ARID2 | GWAS association (p=1.0e-22) | Large GWAS |
| rs72845663 | GBF1 | GWAS association (p=3.0e-22) | Large GWAS |
| rs28436726 | — | GWAS association (p=4.0e-22) | Large GWAS |
| rs11756438 | CEP85L | GWAS association (p=5.0e-22) | Large GWAS |
| rs10494366 | NOS1AP | GWAS association (p=5.0e-22) | Large GWAS |
| rs17608766 | GOSR2 | GWAS association (p=5.0e-22) | Large GWAS |
| rs2273905 | — | GWAS association (p=1.0e-21) | Large GWAS |
| rs12061601 | — | GWAS association (p=3.0e-21) | Large GWAS |
| rs196067 | — | GWAS association (p=4.0e-21) | Large GWAS |
| rs2115630 | ALPK3 | GWAS association (p=1.0e-20) | Large GWAS |
| rs10009824 | LIN54 | GWAS association (p=8.0e-20) | Large GWAS |
| rs4656345 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs76521806 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs145660890 | LOC105377762 | GWAS association (p=1.0e-19) | Large GWAS |
| rs114471407 | HNRNPH1 | GWAS association (p=1.0e-19) | Large GWAS |
| rs7795333 | — | GWAS association (p=1.0e-19) | Large GWAS |
| rs17538328 | CDK13 | GWAS association (p=2.0e-19) | Large GWAS |
| rs72671655 | — | GWAS association (p=1.0e-18) | Large GWAS |
| rs599777 | MAILR | GWAS association (p=2.0e-18) | Large GWAS |
| rs457162 | SLC35F1 | GWAS association (p=3.0e-18) | Large GWAS |
| rs12511815 | — | GWAS association (p=4.0e-18) | Large GWAS |
| rs356131 | — | GWAS association (p=9.0e-18) | Large GWAS |
Showing the top 100 of 421 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.