rs72671655
▶GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (6)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
JT interval
Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)
Allele A
OR 0.08
p 2.0e-25
N 252,730
Large GWAS
European, African unspecified, Hispanic or Latin American, South East Asian, South Asian
natriuretic peptides B proteolytic cleavage product level
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele A
OR 0.12
p 3.0e-22
N 47,745
Large GWAS
European
PR interval
Ntalla I et al. “Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction.” Nature Communications 11(1):2542 (2020)
Allele T
OR 1.73
p 7.0e-22
N 292,566
Large GWAS
multi-ancestry
QT interval
Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)
Allele A
OR 0.07
p 1.0e-18
N 252,730
Large GWAS
European, African unspecified, Hispanic or Latin American, South East Asian, South Asian
Hoffmann TJ et al. “A large genome-wide association study of QT interval length utilizing electronic health records.” Genetics 222(4) (2022)
Allele A
OR 1.28
p 5.0e-8
N 117,532
Large GWAS
multi-ancestry
van Duijvenboden S et al. “Genomic and pleiotropic analyses of resting QT interval identifies novel loci and overlap with atrial electrical disorders.” Human Molecular Genetics 30(24):2513-2523 (2021)
Allele A
OR 0.09
p 1.0e-8
N 24,495
Large GWAS
European
Brugada syndrome
Barc J et al. “Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility.” Nature Genetics 54(3):232-239 (2022)
Allele T
OR 1.85
p 3.0e-13
N 12,821
Large GWAS
European
electrocardiography
Verweij N et al. “The Genetic Makeup of the Electrocardiogram.” Cell Systems 11(3):229-238.e5 (2020)
Allele T
OR 0.08
p 2.0e-8
N 63,706
Major Consortium StudyLarge GWAS
European, NR
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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