Trait

SNPs associated with PR interval

343 genetic variants across 91 genes have been associated with PR interval in published research. Key genes include ADGRL3, AFF1, AKAP6.

Associated variants343 total

rsidGeneEffectEvidence
rs6599250SCN10AGWAS association (p=4.0e-242)Meta-analysis
rs11708996SCN5AGWAS association (p=1.0e-68)Meta-analysis
rs343849—GWAS association (p=3.0e-61)Meta-analysis
rs35712872—GWAS association (p=2.0e-54)Meta-analysis
rs6441111—GWAS association (p=1.0e-51)Meta-analysis
rs2503715—GWAS association (p=1.0e-51)Meta-analysis
rs17287293LOC105369698GWAS association (p=2.0e-41)Meta-analysis
rs1896312—GWAS association (p=1.0e-34)Meta-analysis
rs4430933—GWAS association (p=5.0e-30)Meta-analysis
rs11773845CAV1GWAS association (p=9.0e-28)Meta-analysis
rs3856447—GWAS association (p=1.0e-26)Meta-analysis
rs718426—GWAS association (p=3.0e-24)Meta-analysis
rs13111293—GWAS association (p=6.0e-21)Meta-analysis
rs255292—GWAS association (p=6.0e-21)Meta-analysis
rs9590974LRCH1GWAS association (p=1.0e-19)Meta-analysis
rs12257568—GWAS association (p=6.0e-18)Meta-analysis
rs13087058—GWAS association (p=6.0e-17)Meta-analysis
rs6489953—GWAS association (p=2.0e-16)Meta-analysis
rs12359272—GWAS association (p=4.0e-16)Meta-analysis
rs2585897—GWAS association (p=9.0e-16)Meta-analysis
rs2732860—GWAS association (p=3.0e-15)Meta-analysis
rs2129561—GWAS association (p=3.0e-15)Meta-analysis
rs75013985—GWAS association (p=1.0e-13)Meta-analysis
rs10842383—GWAS association (p=6.0e-13)Meta-analysis
rs17767398SIPA1L1-AS1GWAS association (p=6.0e-13)Meta-analysis
rs6724747MEIS1GWAS association (p=8.0e-13)Meta-analysis
rs29797BNIP1GWAS association (p=5.0e-12)Meta-analysis
rs11840168MICU2GWAS association (p=7.0e-12)Meta-analysis
rs1984481—GWAS association (p=1.0e-11)Meta-analysis
rs13018106—GWAS association (p=2.0e-11)Meta-analysis
rs922984TTNGWAS association (p=2.0e-11)Meta-analysis
rs9534461LRCH1GWAS association (p=1.0e-10)Meta-analysis
rs7729395—GWAS association (p=1.0e-10)Meta-analysis
rs11763856—GWAS association (p=4.0e-10)Meta-analysis
rs12678719ZFPM2GWAS association (p=4.0e-10)Meta-analysis
rs6489973—GWAS association (p=5.0e-10)Meta-analysis
rs4648819—GWAS association (p=5.0e-10)Meta-analysis
rs881301—GWAS association (p=5.0e-10)Meta-analysis
rs11264339—GWAS association (p=6.0e-10)Meta-analysis
rs397637—GWAS association (p=7.0e-10)Meta-analysis
rs11465506—GWAS association (p=7.0e-10)Meta-analysis
rs12127701—GWAS association (p=2.0e-09)Meta-analysis
rs1372797—GWAS association (p=2.0e-09)Meta-analysis
rs17446418—GWAS association (p=3.0e-09)Meta-analysis
rs900669FRMD4BGWAS association (p=6.0e-09)Meta-analysis
rs8019721SIPA1L1GWAS association (p=1.0e-08)Meta-analysis
rs7538988—GWAS association (p=1.0e-08)Meta-analysis
rs11067773—GWAS association (p=1.0e-08)Meta-analysis
rs4461368—GWAS association (p=2.0e-08)Meta-analysis
rs9826413—GWAS association (p=2.0e-08)Meta-analysis
rs16858828—GWAS association (p=2.0e-08)Meta-analysis
rs7638853—GWAS association (p=2.0e-08)Meta-analysis
rs4901308—GWAS association (p=2.0e-08)Meta-analysis
rs3733409FAT1GWAS association (p=3.0e-08)Meta-analysis
rs652673—GWAS association (p=4.0e-08)Meta-analysis
rs904974—GWAS association (p=5.0e-08)Meta-analysis
rs6801957SCN10AGWAS association (p=0.0e+00)Meta-analysis
rs3807989CAV1GWAS association (p=3.0e-194)Meta-analysis
rs2624021ARHGAP24GWAS association (p=2.0e-178)Large GWAS
rs4246224LOC105369698GWAS association (p=2.0e-138)Large GWAS
rs3891585MEIS1GWAS association (p=8.0e-96)Large GWAS
rs6800541SCN10AGWAS association (p=2.0e-74)Large GWAS
rs1124477—GWAS association (p=3.0e-69)Large GWAS
rs6730558LOC105373411GWAS association (p=6.0e-68)Large GWAS
rs6795970SCN10AGWAS association (p=1.0e-58)Large GWAS
rs2754171MYH7GWAS association (p=5.0e-55)Large GWAS
rs29795—GWAS association (p=5.0e-55)Large GWAS
rs11153730—GWAS association (p=3.0e-54)Large GWAS
rs10883908—GWAS association (p=5.0e-52)Large GWAS
rs12869776MICU2GWAS association (p=1.0e-51)Large GWAS
rs116532272—GWAS association (p=7.0e-49)Large GWAS
rs3922844SCN5AGWAS association (p=5.0e-43)Large GWAS
rs4245338LRCH1GWAS association (p=4.0e-35)Large GWAS
rs2732814TMEM182GWAS association (p=4.0e-34)Large GWAS
rs4677294—GWAS association (p=5.0e-34)Large GWAS
rs61989382SIPA1L1GWAS association (p=1.0e-31)Large GWAS
rs35680304—GWAS association (p=4.0e-31)Large GWAS
rs10882644ALDH18A1GWAS association (p=9.0e-31)Large GWAS
rs114555443PAMGWAS association (p=2.0e-29)Large GWAS
rs2042995TTNGWAS association (p=8.0e-28)Large GWAS
rs59212267THRBGWAS association (p=4.0e-27)Large GWAS
rs60325252THRBGWAS association (p=9.0e-27)Large GWAS
rs1531447—GWAS association (p=4.0e-26)Large GWAS
rs72690486FAF1GWAS association (p=1.0e-25)Large GWAS
rs4834347—GWAS association (p=2.0e-25)Large GWAS
rs4971089KRTCAP2GWAS association (p=2.0e-25)Large GWAS
rs17496249—GWAS association (p=1.0e-23)Large GWAS
rs10039283—GWAS association (p=3.0e-23)Large GWAS
rs340397—GWAS association (p=6.0e-22)Large GWAS
rs72671655—GWAS association (p=7.0e-22)Large GWAS
rs4975572—GWAS association (p=6.0e-21)Large GWAS
rs13131421—GWAS association (p=3.0e-20)Large GWAS
rs7692808ARHGAP24GWAS association (p=6.0e-20)Large GWAS
rs1895585TBX5GWAS association (p=1.0e-19)Large GWAS
rs6795775FRMD4BGWAS association (p=1.0e-19)Large GWAS
rs6442433—GWAS association (p=2.0e-19)Large GWAS
rs2004851—GWAS association (p=2.0e-19)Large GWAS
rs881299—GWAS association (p=3.0e-19)Large GWAS
rs7394152SYNPO2L-AS1GWAS association (p=3.0e-19)Large GWAS
rs7374004—GWAS association (p=3.0e-19)Large GWAS

Showing the top 100 of 343 variants by evidence strength.

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.

PR interval — SNPs & genetic associations — Gene Wizard