SIPA1L1

signal induced proliferation associated 1 like 1

Summary

Predicted to enable GTPase activator activity; actin filament binding activity; and protein kinase binding activity. Predicted to be involved in several processes, including activation of GTPase activity; ephrin receptor signaling pathway; and regulation of postsynapse organization. Located in actin cytoskeleton and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Known Variants114 total

rsidPosition (GRCh37)AllelesClassClinVar
rs801972114:71,834,210G/Aintron variant—
rs3499178114:71,921,576G/Aregulatory region variant—
rs1212714:71,956,270T/Cintron variant—
rs6198938214:71,983,638T/A——
rs1115890714:71,987,065A/T——
rs13918841514:72,054,606G/A—uncertain significance
rs129722133414:72,054,698C/T—uncertain significance
rs14648339414:72,054,702G/A—uncertain significance
rs74617022514:72,054,707C/T—uncertain significance
rs7862120914:72,054,708A/G—benign
rs37327232014:72,054,717A/T—uncertain significance
rs1288463814:72,054,755A/C—benign
rs14895869514:72,054,759C/A—likely benign
rs75640894414:72,054,784A/G—uncertain significance
rs14802246514:72,054,786C/A—uncertain significance
rs86853794214:72,054,870G/A—uncertain significance
rs76102209214:72,054,980A/G—uncertain significance
rs203484828414:72,054,990G/T—uncertain significance
rs14809365214:72,055,017C/T—uncertain significance
rs14109410414:72,055,024G/A—likely benign
rs250660329014:72,055,041C/T—uncertain significance
rs14751465814:72,055,078C/G—benign
rs75410403014:72,055,086C/G—uncertain significance
rs250660950814:72,055,121A/G—uncertain significance
rs13843653514:72,055,185G/T—uncertain significance
rs203487450814:72,055,221C/T—uncertain significance
rs250662017214:72,055,262T/G—uncertain significance
rs14927882814:72,055,335C/T—uncertain significance
rs77749947114:72,055,394A/G—uncertain significance
rs78113287814:72,055,406A/G—uncertain significance
rs75906583614:72,055,448A/G—uncertain significance
rs185964314:72,055,468A/C—benign
rs250664527014:72,055,517T/G—uncertain significance
rs75125073414:72,055,558G/T—uncertain significance
rs124361927514:72,055,604A/G—uncertain significance
rs14525409514:72,055,641A/G—uncertain significance
rs14745445814:72,055,745A/T—uncertain significance
rs37069645214:72,055,748G/A—uncertain significance
rs1184878514:72,057,355G/Aintron variant—
rs55100146514:72,082,223G/A——
rs87922030314:72,085,498A/T—uncertain significance
rs36992001114:72,090,800C/T—likely benign
rs11308266414:72,090,809G/A—benign
rs14594377414:72,090,824G/A—likely benign
rs250849759014:72,090,889G/C—uncertain significance
rs120638129214:72,090,906A/G—uncertain significance
rs77606313114:72,090,907A/G—uncertain significance
rs37000538114:72,117,176G/A—uncertain significance
rs115948112714:72,125,137C/T—uncertain significance
rs147103208314:72,128,040G/A—uncertain significance
rs14261956014:72,128,131C/T—benign
rs130478518914:72,128,162T/C—uncertain significance
rs20223709314:72,128,170C/A—uncertain significance
rs139295804414:72,128,178G/A—uncertain significance
rs74936133714:72,137,859A/G—uncertain significance
rs78075017414:72,137,937C/T—uncertain significance
rs130763878214:72,138,006G/A—uncertain significance
rs14460344914:72,138,056A/G—uncertain significance
rs14541193214:72,138,146A/G—uncertain significance
rs77681460614:72,138,155A/G—uncertain significance
rs14335339414:72,138,183A/G—uncertain significance
rs14458908314:72,138,209C/G—uncertain significance
rs76494455414:72,138,263G/A—uncertain significance
rs250989406514:72,138,293A/G—uncertain significance
rs14316905614:72,138,320C/G—uncertain significance
rs122377271414:72,138,326A/G—uncertain significance
rs20216904614:72,138,356G/T—uncertain significance
rs13982709014:72,139,170C/T—uncertain significance
rs431969814:72,147,443G/Aintron variant—
rs37337914914:72,152,093C/G—uncertain significance
rs37399393914:72,152,098C/T—uncertain significance
rs14110611114:72,152,099G/T—uncertain significance
rs124858208414:72,152,131G/A—uncertain significance
rs3410893714:72,152,241G/T—uncertain significance
rs56580509214:72,152,298C/T—likely benign
rs144786430114:72,165,719C/G—uncertain significance
rs20060567614:72,165,762C/T—uncertain significance
rs76654224414:72,169,109G/A—uncertain significance
rs7837599214:72,169,152A/G—likely benign
rs104145573214:72,171,474T/C—uncertain significance
rs20208017014:72,171,995C/T—uncertain significance
rs75030584114:72,172,043A/T—uncertain significance
rs104077510914:72,172,053G/A—uncertain significance
rs75776255414:72,176,135C/T—uncertain significance
rs75176393214:72,176,233C/T—uncertain significance
rs76794297514:72,176,236A/T—uncertain significance
rs20023623414:72,176,258G/T—uncertain significance
rs14668574414:72,176,315C/G—uncertain significance
rs75455427114:72,176,327C/T—uncertain significance
rs54170327214:72,182,606A/G——
rs75653046714:72,190,378G/A—uncertain significance
rs77221290414:72,190,381A/G—uncertain significance
rs208395815914:72,190,398G/T—uncertain significance
rs208395928314:72,190,405C/T—uncertain significance
rs20162420014:72,190,414G/A—uncertain significance
rs123082681914:72,190,425A/G—uncertain significance
rs132313408114:72,190,581G/A—uncertain significance
rs75301091414:72,190,597C/T—uncertain significance
rs103807969914:72,191,409G/A—uncertain significance
rs76585868814:72,191,430C/T—uncertain significance

Showing 100 of 114 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.