rs10842383
▶GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (3)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
atrial fibrillation
Roselli C et al. “Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.” Nature Genetics 57(3):539-547 (2025)
Allele C
OR 1.10
p 2.0e-57
N 1,650,345
Meta-analysisLarge GWAS
multi-ancestry
Miyazawa K et al. “Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.” Nature Genetics 55(2):187-197 (2023)
Allele C
OR 0.11
p 2.0e-35
N 2,339,188
Large GWAS
multi-ancestry
Koskeridis F et al. “Multi-trait association analysis reveals shared genetic loci between Alzheimer's disease and cardiovascular traits.” Nature Communications 15(1):9827 (2024)
Allele C
OR 0.02
p 2.0e-24
N 1,486,094
Large GWAS
European
Roselli C et al. “Multi-ethnic genome-wide association study for atrial fibrillation.” Nature Genetics 50(9):1225-1233 (2018)
Allele C
OR 1.11
p 1.0e-25
N 588,190
Large GWAS
multi-ancestry
PR interval
van Setten J et al. “Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits.” European Journal of Human Genetics : Ejhg 27(6):952-962 (2019)
Allele T
OR 1.88
p 6.0e-13
N 31,695
Meta-analysisLarge GWAS
multi-ancestry
heart rate variability measurement
Nolte IM et al. “Genetic loci associated with heart rate variability and their effects on cardiac disease risk.” Nature Communications 8:15805 (2017)
Allele C
OR 0.05
p 9.0e-31
N 27,850
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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