Trait
SNPs associated with Brugada syndrome
38 genetic variants across 11 genes have been associated with Brugada syndrome in published research. Key genes include CAMK2D, GATA4, HEY2.
Associated variants38 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs6801957 | SCN10A | GWAS association (p=6.0e-217) | Large GWAS |
| rs10428132 | SCN10A | GWAS association (p=1.0e-68) | Large GWAS |
| rs3757217 | HEY2 | GWAS association (p=4.0e-57) | Large GWAS |
| rs7374540 | — | GWAS association (p=4.0e-57) | Large GWAS |
| rs6782237 | — | GWAS association (p=1.0e-47) | Large GWAS |
| rs9398791 | NCOA7 | GWAS association (p=1.0e-39) | Large GWAS |
| rs7433206 | SCN5A | GWAS association (p=1.0e-23) | Large GWAS |
| rs34760424 | — | GWAS association (p=3.0e-23) | Large GWAS |
| rs9388446 | HEY2-AS1 | GWAS association (p=2.0e-21) | Large GWAS |
| rs9388451 | — | GWAS association (p=5.0e-17) | Large GWAS |
| rs6810361 | — | GWAS association (p=4.0e-16) | Large GWAS |
| rs41310232 | SCN5A | GWAS association (p=1.0e-15) | Large GWAS |
| rs11708996 | SCN5A | GWAS association (p=1.0e-14) | Large GWAS |
| rs62241190 | — | GWAS association (p=9.0e-14) | Large GWAS |
| rs16835523 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs883079 | TBX5 | GWAS association (p=3.0e-13) | Large GWAS |
| rs72671655 | — | GWAS association (p=3.0e-13) | Large GWAS |
| rs72622262 | — | GWAS association (p=2.0e-12) | Large GWAS |
| rs76267029 | — | GWAS association (p=3.0e-11) | Large GWAS |
| rs11765936 | — | GWAS association (p=4.0e-11) | Large GWAS |
| rs476348 | — | GWAS association (p=6.0e-11) | Large GWAS |
| rs7105159 | — | GWAS association (p=8.0e-11) | Large GWAS |
| rs804281 | GATA4 | GWAS association (p=1.0e-09) | Large GWAS |
| rs11645463 | — | GWAS association (p=1.0e-09) | Large GWAS |
| rs340398 | — | GWAS association (p=2.0e-09) | Large GWAS |
| rs72905083 | WT1-AS | GWAS association (p=2.0e-09) | Large GWAS |
| rs133902 | MYO18B | GWAS association (p=5.0e-09) | Large GWAS |
| rs2593619 | USP34 | GWAS association (p=7.0e-09) | Large GWAS |
| rs2336244 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs1379553 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6913204 | — | GWAS association (p=1.0e-08) | Large GWAS |
| rs6816233 | CAMK2D | GWAS association (p=2.0e-08) | Large GWAS |
| rs12945884 | — | GWAS association (p=2.0e-08) | Large GWAS |
| rs3746448 | — | GWAS association (p=3.0e-08) | Large GWAS |
| rs7638909 | SCN5A | GWAS association (p=3.0e-08) | Large GWAS |
| rs3792723 | — | GWAS association (p=5.0e-08) | Large GWAS |
| rs6767797 | — | GWAS association (p=3.0e-10) | Small GWAS |
| rs3734634 | — | GWAS association (p=8.0e-09) | Small GWAS |
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.