rs56078134

This variant is located in the SLC12A7 gene.

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GWAS Catalog Trait Associations (2)

Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.

JT interval

Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)

Allele A

OR 0.03

p 5.0e-29

N 252,730

Large GWAS

European, African unspecified, Hispanic or Latin American, South East Asian, South Asian

QT interval

Young WJ et al. “Genetic analyses of the electrocardiographic QT interval and its components identify additional loci and pathways.” Nature Communications 13(1):5144 (2022)

Allele A

OR 0.03

p 1.0e-27

N 252,730

Large GWAS

European, African unspecified, Hispanic or Latin American, South East Asian, South Asian

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ClinVar annotation

Benign★★★☆

2 submitters1 publication

View on ClinVar →

About SLC12A7

Enables protein kinase binding activity. Predicted to be involved in several processes, including chloride ion homeostasis; monoatomic ion transmembrane transport; and potassium ion homeostasis. Part of protein-containing complex. [provided by Alliance of Genome Resources, Jul 2025]