ANKRD12

ankyrin repeat domain 12

Summary

This gene encodes a member of the ankyrin repeats-containing cofactor family. These proteins may inhibit the transcriptional activity of nuclear receptors through the recruitment of histone deacetylases. The encoded protein interacts with p160 coactivators and also represses transcription mediated by the coactivator alteration/deficiency in activation 3 (ADA3). Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Feb 2011]

Known Variants98 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs545789536	18:9,159,728	C/T	—	—
rs11660889	18:9,177,297	C/A	—	—
rs1457154804	18:9,182,494	G/T	—	uncertain significance
rs1487608988	18:9,182,516	A/C	—	uncertain significance
rs527890099	18:9,191,860	A/C	—	—
rs1283653589	18:9,195,553	A/G	—	uncertain significance
rs746788208	18:9,195,615	A/G	—	uncertain significance
rs767266765	18:9,204,488	C/T	—	uncertain significance
rs754371932	18:9,204,502	T/G	—	uncertain significance
rs372921602	18:9,208,669	G/C	—	uncertain significance
rs2510619576	18:9,208,686	A/C	—	uncertain significance
rs753281159	18:9,208,720	A/G	—	uncertain significance
rs761946926	18:9,211,651	A/C	—	uncertain significance
rs2510640185	18:9,211,672	G/T	—	uncertain significance
rs1053588385	18:9,221,931	A/G	—	uncertain significance
rs142598284	18:9,254,236	C/T	—	uncertain significance
rs755916069	18:9,254,511	C/A	—	uncertain significance
rs372227176	18:9,254,644	A/G	—	uncertain significance
rs900435043	18:9,254,824	A/G	—	uncertain significance
rs774563249	18:9,254,830	G/A	—	uncertain significance
rs2510849897	18:9,254,835	T/A	—	uncertain significance
rs199503455	18:9,254,836	C/G	—	uncertain significance
rs762873466	18:9,254,875	A/G	—	uncertain significance
rs888654625	18:9,254,884	C/T	—	uncertain significance
rs2510851408	18:9,255,001	A/T	—	uncertain significance
rs148294667	18:9,255,003	C/A	—	uncertain significance
rs755422876	18:9,255,022	C/G	—	uncertain significance
rs141484109	18:9,255,081	A/G	—	likely benign
rs1368228720	18:9,255,082	G/A	—	likely benign
rs2038522130	18:9,255,088	A/T	—	uncertain significance
rs748111493	18:9,255,163	T/G	—	uncertain significance
rs763412806	18:9,255,283	A/C	—	uncertain significance
rs757263111	18:9,255,301	A/G	—	likely benign
rs977914828	18:9,255,313	A/G	—	uncertain significance
rs374546403	18:9,255,315	G/C	—	uncertain significance
rs202094593	18:9,255,451	A/C	—	uncertain significance
rs115155142	18:9,255,499	G/A	—	uncertain significance
rs1193650458	18:9,255,594	A/G	—	likely benign
rs1422593766	18:9,255,628	T/G	—	uncertain significance
rs864622035	18:9,255,858	G/T	—	uncertain significance
rs562237152	18:9,255,928	G/A	—	uncertain significance
rs202164347	18:9,255,963	A/G	—	uncertain significance
rs551699901	18:9,256,011	C/T	—	uncertain significance
rs1177126587	18:9,256,062	A/G	—	uncertain significance
rs371280033	18:9,256,084	A/G	—	uncertain significance
rs2510865998	18:9,256,162	A/C	—	uncertain significance
rs182642815	18:9,256,189	C/A	—	likely benign
rs186915035	18:9,256,216	C/T	—	uncertain significance
rs143532549	18:9,256,299	C/A	—	uncertain significance
rs151012938	18:9,256,405	C/A	—	uncertain significance
rs2510869815	18:9,256,410	G/A	—	uncertain significance
rs2510870927	18:9,256,501	G/A	—	uncertain significance
rs76101082	18:9,256,557	C/T	—	uncertain significance
rs138287524	18:9,256,617	C/T	—	uncertain significance
rs2510873387	18:9,256,702	T/C	—	uncertain significance
rs767440381	18:9,256,756	C/T	—	uncertain significance
rs201690826	18:9,256,786	C/T	—	uncertain significance
rs375166107	18:9,256,789	T/C	—	uncertain significance
rs1353650699	18:9,256,797	T/G	—	uncertain significance
rs773669961	18:9,257,184	G/A	—	uncertain significance
rs2510879381	18:9,257,223	A/G	—	uncertain significance
rs768524498	18:9,257,232	T/C	—	uncertain significance
rs373743530	18:9,257,277	G/C	—	uncertain significance
rs371458043	18:9,257,346	A/G	—	uncertain significance
rs139071340	18:9,257,349	G/T	—	uncertain significance
rs377492566	18:9,257,358	A/G	—	uncertain significance
rs146120223	18:9,257,430	A/G	—	uncertain significance
rs2145213497	18:9,257,452	A/G	—	likely benign
rs2510882678	18:9,257,482	A/C	—	uncertain significance
rs776379006	18:9,257,493	C/G	—	uncertain significance
rs148325300	18:9,257,557	C/G	—	uncertain significance
rs141465808	18:9,257,577	A/G	—	likely benign
rs1313431404	18:9,257,613	A/G	—	likely benign
rs1226143967	18:9,257,701	C/T	—	uncertain significance
rs367860292	18:9,257,724	C/T	—	uncertain significance
rs143090707	18:9,257,792	G/A	—	uncertain significance
rs200122107	18:9,257,802	T/C	—	uncertain significance
rs187403892	18:9,257,813	T/A	—	uncertain significance
rs978805081	18:9,257,925	G/A	—	uncertain significance
rs146159815	18:9,257,934	A/C	—	uncertain significance
rs756222159	18:9,257,963	C/G	—	likely benign
rs1387038519	18:9,257,982	T/C	—	uncertain significance
rs201049162	18:9,258,088	A/G	—	uncertain significance
rs576647084	18:9,258,096	T/G	—	uncertain significance
rs2510890888	18:9,258,101	G/C	—	uncertain significance
rs139559099	18:9,258,208	G/A	—	uncertain significance
rs755876473	18:9,258,300	T/A	—	uncertain significance
rs372100647	18:9,258,309	A/G	—	uncertain significance
rs1409202613	18:9,258,343	C/G	—	uncertain significance
rs760017982	18:9,258,358	A/T	—	uncertain significance
rs770241086	18:9,258,469	T/C	—	uncertain significance
rs148963819	18:9,258,516	C/G	—	uncertain significance
rs76591416	18:9,258,592	A/G	—	uncertain significance
rs1412905078	18:9,258,637	G/A	—	uncertain significance
rs2038787898	18:9,258,667	C/G	—	uncertain significance
rs762746236	18:9,258,690	A/G	—	uncertain significance
rs190468609	18:9,258,814	G/A	—	uncertain significance
rs1382767523	18:9,279,557	G/A	—	uncertain significance

Gene information from NCBI Gene. Variant classifications from ClinVar.