ANKRD42
ankyrin repeat domain 42
Summary
Predicted to enable NF-kappaB binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to act upstream of or within positive regulation of NF-kappaB transcription factor activity and positive regulation of cytokine production involved in inflammatory response. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants29 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1401510201 | 11:82,909,566 | G/A | — | uncertain significance |
| rs770654416 | 11:82,909,595 | A/G | — | uncertain significance |
| rs2496332982 | 11:82,909,596 | T/C | — | uncertain significance |
| rs553469129 | 11:82,911,007 | T/G | — | — |
| rs763601768 | 11:82,917,149 | C/T | — | uncertain significance |
| rs1181716018 | 11:82,917,194 | A/T | — | uncertain significance |
| rs760939649 | 11:82,921,349 | T/C | — | uncertain significance |
| rs2496373910 | 11:82,921,387 | G/A | — | uncertain significance |
| rs148803266 | 11:82,921,406 | T/G | — | uncertain significance |
| rs2496374269 | 11:82,921,430 | T/C | — | uncertain significance |
| rs576666131 | 11:82,921,439 | A/T | — | uncertain significance |
| rs964807703 | 11:82,921,445 | T/C | — | uncertain significance |
| rs2496378411 | 11:82,922,346 | G/A | — | uncertain significance |
| rs919305719 | 11:82,922,373 | G/A | — | uncertain significance |
| rs929424767 | 11:82,922,398 | G/A | — | uncertain significance |
| rs140132570 | 11:82,922,427 | T/C | — | uncertain significance |
| rs149777015 | 11:82,935,966 | C/T | — | uncertain significance |
| rs764029903 | 11:82,935,984 | T/C | — | uncertain significance |
| rs376999354 | 11:82,935,987 | A/G | — | uncertain significance |
| rs754543450 | 11:82,936,011 | A/C | — | uncertain significance |
| rs145605968 | 11:82,936,046 | C/A | — | uncertain significance |
| rs780249161 | 11:82,938,823 | G/C | — | uncertain significance |
| rs374797808 | 11:82,938,858 | A/T | — | uncertain significance |
| rs536189501 | 11:82,938,882 | G/A | — | uncertain significance |
| rs141499620 | 11:82,950,006 | G/A | intron variant | — |
| rs2549990971 | 11:82,951,835 | G/A | — | uncertain significance |
| rs765366717 | 11:82,951,862 | G/A | — | uncertain significance |
| rs369768778 | 11:82,951,874 | G/C | — | uncertain significance |
| rs772669072 | 11:82,951,958 | G/T | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.