rs553469129
This variant is located in the ANKRD42 gene.
▶GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (1)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
adverse effect, response to stimulus
Verma A et al. “Diversity and scale: Genetic architecture of 2068 traits in the VA Million Veteran Program.” Science (new York, N.y.) 385(6706):eadj1182 (2024)
Allele T
OR 2.64
p 8.0e-13
N 567,149
Major Consortium StudyLarge GWAS
multi-ancestry
About ANKRD42
Predicted to enable NF-kappaB binding activity and cyclin-dependent protein serine/threonine kinase inhibitor activity. Predicted to act upstream of or within positive regulation of NF-kappaB transcription factor activity and positive regulation of cytokine production involved in inflammatory response. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]
View all ANKRD42 variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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