ARPC2
actin related protein 2/3 complex subunit 2
Summary
This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined. [provided by RefSeq, Jul 2008]
Known Variants16 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs13403276 | 2:219,081,297 | T/C | upstream gene variant | — |
| rs144937426 | 2:219,082,200 | C/T | — | benign |
| rs769151697 | 2:219,082,250 | C/A | — | uncertain significance |
| rs6733051 | 2:219,084,533 | C/G | — | — |
| rs114225066 | 2:219,090,287 | G/A | intron variant | — |
| rs1176000008 | 2:219,090,659 | G/A | — | uncertain significance |
| rs199578440 | 2:219,099,093 | G/A | — | uncertain significance |
| rs147649871 | 2:219,103,525 | A/G | — | uncertain significance |
| rs764236963 | 2:219,104,165 | T/G | — | uncertain significance |
| rs189047226 | 2:219,104,332 | T/C | intron variant | — |
| rs17653757 | 2:219,109,364 | G/A | — | — |
| rs1041935451 | 2:219,110,188 | C/G | — | uncertain significance |
| rs13015410 | 2:219,110,721 | G/C | — | — |
| rs74349827 | 2:219,114,084 | C/T | — | benign |
| rs188696608 | 2:219,114,608 | G/A | — | uncertain significance |
| rs6736362 | 2:219,115,108 | C/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.