C20orf203
chromosome 20 open reading frame 203
Summary
The protein encoded by this gene is thought to be a human-specific protein. Currently available evidence suggests that orthologous regions in other organisms contain sequence differences that would not support production of a protein product. Genome-wide association studies have suggested the possibility that a SNP in the 3' UTR, rs17123507, could be associated with nicotine addiction. Expression of this gene may be elevated in some individuals with Alzheimer's disease. [provided by RefSeq, Mar 2017]
Known Variants11 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs6141766 | 20:31,222,769 | A/G | regulatory region variant | — |
| rs770340275 | 20:31,230,433 | C/T | — | — |
| rs35103329 | 20:31,238,139 | G/A | coding sequence variant | — |
| rs764433662 | 20:31,238,244 | A/G | — | uncertain significance |
| rs750670496 | 20:31,238,559 | G/A | — | uncertain significance |
| rs766563811 | 20:31,238,589 | T/G | — | uncertain significance |
| rs13036962 | 20:31,239,010 | T/G | — | — |
| rs6058796 | 20:31,255,829 | C/T | intron variant | — |
| rs6141779 | 20:31,259,366 | C/T | intron variant | — |
| rs6141333 | 20:31,263,324 | C/T | — | — |
| rs6141781 | 20:31,263,342 | C/T | upstream gene variant | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.