Trait
SNPs associated with Systolic blood pressure
4068 genetic variants across 737 genes have been associated with Systolic blood pressure in published research. Key genes include ABCB11, ABCC8, ABHD17C.
Associated variants4,068 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12509595 | — | GWAS association (p=8.0e-133) | Meta-analysis |
| rs11191580 | NT5C2 | GWAS association (p=1.0e-111) | Meta-analysis |
| rs17249754 | ATP2B1 | GWAS association (p=8.0e-20) | Meta-analysis |
| rs167479 | — | GWAS association (p=6.0e-82) | Meta-analysis |
| rs12579302 | — | GWAS association (p=9.0e-72) | Meta-analysis |
| rs7302981 | — | GWAS association (p=2.0e-47) | Meta-analysis |
| rs11977526 | LOC102723446 | GWAS association (p=1.0e-40) | Meta-analysis |
| rs11066280 | HECTD4 | GWAS association (p=8.0e-31) | Meta-analysis |
| rs891511 | — | GWAS association (p=5.0e-28) | Meta-analysis |
| rs699 | AGT | Elevated systolic blood pressure | Meta-analysis |
| rs11191548 | CNNM2 | GWAS association (p=7.0e-24) | Meta-analysis |
| rs181200083 | SORCS3 | GWAS association (p=1.0e-21) | Meta-analysis |
| rs2306899 | DDHD2 | GWAS association (p=9.0e-21) | Meta-analysis |
| rs2320299 | — | GWAS association (p=9.0e-21) | Meta-analysis |
| rs2493292 | PRDM16 | GWAS association (p=2.0e-20) | Meta-analysis |
| rs4574 | — | GWAS association (p=7.0e-19) | Meta-analysis |
| rs277152 | — | GWAS association (p=3.0e-18) | Meta-analysis |
| rs7412 | APOE | GWAS association (p=4.0e-18) | Meta-analysis |
| rs535313355 | SORCS3 | GWAS association (p=1.0e-17) | Meta-analysis |
| rs8068318 | TBX2 | GWAS association (p=2.0e-17) | Meta-analysis |
| rs7756992 | CDKAL1 | GWAS association (p=4.0e-17) | Meta-analysis |
| rs3743157 | — | GWAS association (p=9.0e-17) | Meta-analysis |
| rs366178 | — | GWAS association (p=1.0e-16) | Meta-analysis |
| rs34071855 | — | GWAS association (p=2.0e-16) | Meta-analysis |
| rs10440833 | CDKAL1 | GWAS association (p=3.0e-16) | Meta-analysis |
| rs556058784 | — | GWAS association (p=5.0e-16) | Meta-analysis |
| rs4691380 | PDGFC | GWAS association (p=7.0e-16) | Meta-analysis |
| rs801171 | LOC105378198 | GWAS association (p=1.0e-15) | Meta-analysis |
| rs576629818 | — | GWAS association (p=1.0e-15) | Meta-analysis |
| rs2328813 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs142760284 | — | GWAS association (p=2.0e-15) | Meta-analysis |
| rs4626664 | PTPRD | GWAS association (p=3.0e-15) | Meta-analysis |
| rs4712524 | CDKAL1 | GWAS association (p=3.0e-15) | Meta-analysis |
| rs10946398 | CDKAL1 | GWAS association (p=3.0e-15) | Meta-analysis |
| rs75337836 | — | GWAS association (p=3.0e-15) | Meta-analysis |
| rs4731702 | LOC105375508 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs972283 | LOC105375508 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs4712523 | CDKAL1 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs7754840 | CDKAL1 | GWAS association (p=5.0e-15) | Meta-analysis |
| rs975730 | — | GWAS association (p=8.0e-15) | Meta-analysis |
| rs2280560 | CLDN23 | GWAS association (p=1.0e-14) | Meta-analysis |
| rs73181210 | PHC3 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs459193 | C5orf67 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs9686661 | C5orf67 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs540369678 | SORCS3 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs7076147 | — | GWAS association (p=2.0e-14) | Meta-analysis |
| rs1167827 | — | GWAS association (p=3.0e-14) | Meta-analysis |
| rs9295474 | CDKAL1 | GWAS association (p=3.0e-14) | Meta-analysis |
| rs143057152 | NR3C2 | GWAS association (p=4.0e-14) | Meta-analysis |
| rs2251860 | — | GWAS association (p=4.0e-14) | Meta-analysis |
| rs704 | VTN | GWAS association (p=6.0e-14) | Meta-analysis |
| rs3821845 | CACNA1D | GWAS association (p=8.0e-14) | Meta-analysis |
| rs2044693 | — | GWAS association (p=2.0e-13) | Meta-analysis |
| rs184289122 | CFAP58 | GWAS association (p=2.0e-13) | Meta-analysis |
| rs4731112 | — | GWAS association (p=3.0e-13) | Meta-analysis |
| rs76767219 | — | GWAS association (p=4.0e-13) | Meta-analysis |
| rs12478601 | THADA | GWAS association (p=4.0e-13) | Meta-analysis |
| rs6822892 | — | GWAS association (p=4.0e-13) | Meta-analysis |
| rs7838433 | — | GWAS association (p=5.0e-13) | Meta-analysis |
| rs782513 | — | GWAS association (p=6.0e-13) | Meta-analysis |
| rs11897119 | MEIS1 | GWAS association (p=6.0e-13) | Meta-analysis |
| rs17428471 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs4265150 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs3822346 | — | GWAS association (p=2.0e-12) | Meta-analysis |
| rs4846567 | — | GWAS association (p=3.0e-12) | Meta-analysis |
| rs1434536 | BMPR1B | GWAS association (p=3.0e-12) | Meta-analysis |
| rs200383755 | GATA5 | GWAS association (p=3.0e-12) | Meta-analysis |
| rs4639796 | — | GWAS association (p=4.0e-12) | Meta-analysis |
| rs5219 | KCNJ11 | Elevated systolic blood pressure | Meta-analysis |
| rs642961 | — | GWAS association (p=6.0e-12) | Meta-analysis |
| rs2843744 | — | GWAS association (p=6.0e-12) | Meta-analysis |
| rs2240694 | PCDHA3 | GWAS association (p=7.0e-12) | Meta-analysis |
| rs284844 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs246074 | PCDHA9 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs9373523 | STXBP5 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs2257205 | RNF43 | GWAS association (p=1.0e-11) | Meta-analysis |
| rs12543567 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs13078807 | CADM2 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs2153960 | FOXO3 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs27044 | ERAP1 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs26653 | ERAP1 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs4705752 | MCC | GWAS association (p=2.0e-11) | Meta-analysis |
| rs117627418 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs41284185 | — | GWAS association (p=2.0e-11) | Meta-analysis |
| rs2270860 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs179993 | — | GWAS association (p=3.0e-11) | Meta-analysis |
| rs9486916 | — | GWAS association (p=4.0e-11) | Meta-analysis |
| rs2206734 | CDKAL1 | GWAS association (p=4.0e-11) | Meta-analysis |
| rs4919669 | ARL3 | GWAS association (p=5.0e-11) | Meta-analysis |
| rs2853676 | TERT | GWAS association (p=5.0e-11) | Meta-analysis |
| rs13298768 | — | GWAS association (p=9.0e-11) | Meta-analysis |
| rs12748152 | — | GWAS association (p=1.0e-10) | Meta-analysis |
| rs27434 | ERAP1 | GWAS association (p=1.0e-10) | Meta-analysis |
| rs1138293 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs9683944 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs210381 | — | GWAS association (p=2.0e-10) | Meta-analysis |
| rs2770928 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs2271904 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs5068 | NPPA | GWAS association (p=3.0e-10) | Meta-analysis |
| rs7720317 | LINC02227 | GWAS association (p=3.0e-10) | Meta-analysis |
Showing the top 100 of 4,068 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.