PHC3
polyhomeotic homolog 3
Summary
Predicted to enable chromatin binding activity and histone binding activity. Predicted to be involved in negative regulation of DNA-templated transcription. Located in nucleoplasm. Part of PRC1 complex. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants46 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs781242579 | 3:169,815,034 | G/A | — | uncertain significance |
| rs2473727983 | 3:169,815,129 | A/G | — | likely benign |
| rs758338434 | 3:169,820,389 | C/T | — | uncertain significance |
| rs944861836 | 3:169,820,390 | G/A | — | uncertain significance |
| rs1715697616 | 3:169,820,423 | G/A | — | uncertain significance |
| rs750218946 | 3:169,820,456 | G/A | — | uncertain significance |
| rs537716428 | 3:169,820,612 | G/A | — | uncertain significance |
| rs190320073 | 3:169,820,645 | C/T | — | uncertain significance |
| rs999704054 | 3:169,820,670 | G/A | — | uncertain significance |
| rs759442387 | 3:169,820,695 | A/C | — | uncertain significance |
| rs1409848309 | 3:169,824,732 | T/C | — | uncertain significance |
| rs766198762 | 3:169,831,241 | T/C | — | uncertain significance |
| rs73181210 | 3:169,831,268 | T/C | missense variant | — |
| rs1209034889 | 3:169,835,078 | T/G | — | uncertain significance |
| rs1023402656 | 3:169,835,085 | T/C | — | uncertain significance |
| rs138410529 | 3:169,835,124 | T/A | — | uncertain significance |
| rs750527990 | 3:169,835,130 | T/C | — | uncertain significance |
| rs755639949 | 3:169,835,132 | G/T | — | uncertain significance |
| rs1719237156 | 3:169,835,213 | G/C | — | uncertain significance |
| rs1172893082 | 3:169,846,692 | G/A | — | uncertain significance |
| rs2474063623 | 3:169,846,699 | G/A | — | uncertain significance |
| rs760052030 | 3:169,846,710 | A/G | — | uncertain significance |
| rs371052045 | 3:169,846,728 | A/G | — | uncertain significance |
| rs375964753 | 3:169,846,729 | T/C | — | uncertain significance |
| rs2474065769 | 3:169,846,768 | G/A | — | uncertain significance |
| rs533549331 | 3:169,846,797 | G/C | — | uncertain significance |
| rs2474066546 | 3:169,846,801 | C/T | — | uncertain significance |
| rs746848610 | 3:169,846,894 | C/T | — | uncertain significance |
| rs192074410 | 3:169,846,921 | T/C | — | uncertain significance |
| rs974085373 | 3:169,846,923 | G/C | — | uncertain significance |
| rs1008337706 | 3:169,847,047 | G/C | — | uncertain significance |
| rs1721866735 | 3:169,847,070 | G/C | — | uncertain significance |
| rs746365985 | 3:169,847,103 | G/A | — | uncertain significance |
| rs1721878654 | 3:169,847,130 | C/T | — | uncertain significance |
| rs373115706 | 3:169,847,137 | C/A | — | uncertain significance |
| rs780757485 | 3:169,847,215 | T/C | — | uncertain significance |
| rs1721894060 | 3:169,847,218 | G/C | — | uncertain significance |
| rs761958881 | 3:169,847,250 | A/C | — | uncertain significance |
| rs752650098 | 3:169,847,294 | C/G | — | uncertain significance |
| rs368080049 | 3:169,854,327 | A/C | — | uncertain significance |
| rs749668391 | 3:169,854,357 | T/C | — | uncertain significance |
| rs762319943 | 3:169,854,435 | G/A | — | uncertain significance |
| rs374829799 | 3:169,854,449 | T/C | — | uncertain significance |
| rs34124911 | 3:169,854,671 | T/G | — | — |
| rs2473610039 | 3:169,867,010 | G/A | — | uncertain significance |
| rs758005542 | 3:169,896,577 | T/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.