Trait
SNPs associated with Hypertension
405 genetic variants across 127 genes have been associated with Hypertension in published research. Key genes include ABHD17C, ADCY9, ADD1.
Associated variants405 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs167479 | — | GWAS association (p=2.0e-42) | Meta-analysis |
| rs891511 | — | GWAS association (p=2.0e-22) | Meta-analysis |
| rs72681869 | SOS2 | GWAS association (p=6.0e-17) | Meta-analysis |
| rs4731702 | LOC105375508 | GWAS association (p=1.0e-15) | Meta-analysis |
| rs972283 | LOC105375508 | GWAS association (p=1.0e-15) | Meta-analysis |
| rs459193 | C5orf67 | GWAS association (p=2.0e-14) | Meta-analysis |
| rs2320299 | — | GWAS association (p=1.0e-13) | Meta-analysis |
| rs73181210 | PHC3 | GWAS association (p=3.0e-13) | Meta-analysis |
| rs2306899 | DDHD2 | GWAS association (p=6.0e-13) | Meta-analysis |
| rs143057152 | NR3C2 | GWAS association (p=2.0e-12) | Meta-analysis |
| rs782513 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs1133400 | INPP5A | GWAS association (p=9.0e-11) | Meta-analysis |
| rs4705752 | MCC | GWAS association (p=1.0e-10) | Meta-analysis |
| rs7756992 | CDKAL1 | GWAS association (p=1.0e-10) | Meta-analysis |
| rs2782643 | SZT2 | GWAS association (p=1.0e-10) | Meta-analysis |
| rs9686661 | C5orf67 | GWAS association (p=2.0e-10) | Meta-analysis |
| rs2229840 | NCOR2 | GWAS association (p=2.0e-10) | Meta-analysis |
| rs10440833 | CDKAL1 | GWAS association (p=4.0e-10) | Meta-analysis |
| rs7302981 | — | GWAS association (p=5.0e-10) | Meta-analysis |
| rs277152 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2257205 | RNF43 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs2044693 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs26653 | ERAP1 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs6969780 | HOXA3 | GWAS association (p=2.0e-09) | Meta-analysis |
| rs4937126 | ST3GAL4 | GWAS association (p=2.0e-09) | Meta-analysis |
| rs704 | VTN | GWAS association (p=2.0e-09) | Meta-analysis |
| rs9683944 | — | GWAS association (p=3.0e-09) | Meta-analysis |
| rs117874826 | PLCB3 | GWAS association (p=4.0e-09) | Meta-analysis |
| rs6822892 | — | GWAS association (p=4.0e-09) | Meta-analysis |
| rs28379706 | PLXNB2 | GWAS association (p=4.0e-09) | Meta-analysis |
| rs139600783 | ARHGAP31 | GWAS association (p=5.0e-09) | Meta-analysis |
| rs2206734 | CDKAL1 | GWAS association (p=5.0e-09) | Meta-analysis |
| rs4712524 | CDKAL1 | GWAS association (p=7.0e-09) | Meta-analysis |
| rs10946398 | CDKAL1 | GWAS association (p=8.0e-09) | Meta-analysis |
| rs4691380 | PDGFC | GWAS association (p=9.0e-09) | Meta-analysis |
| rs27434 | ERAP1 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs4712523 | CDKAL1 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs7754840 | CDKAL1 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs9390459 | STXBP5 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs7893462 | ODAD2 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs2504779 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs10490923 | ARMS2 | GWAS association (p=1.0e-08) | Meta-analysis |
| rs3808869 | DCTN3 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs4785340 | ZNF423 | GWAS association (p=2.0e-08) | Meta-analysis |
| rs642961 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs9295474 | CDKAL1 | GWAS association (p=3.0e-08) | Meta-analysis |
| rs366178 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs141325069 | PDE3A | GWAS association (p=4.0e-08) | Meta-analysis |
| rs4846567 | — | GWAS association (p=4.0e-08) | Meta-analysis |
| rs30187 | ERAP1 | GWAS association (p=4.0e-08) | Meta-analysis |
| rs4961 | ADD1 | Increased hypertension risk in Asian populations | Meta-analysis |
| rs1126742 | CYP4A11 | Higher hypertension risk | Meta-analysis |
| rs17782313 | MC4R | Increased hypertension risk | Meta-analysis |
| rs4988235 | MCM6 | Altered blood pressure — no significant causal effect | Meta-analysis |
| rs699 | AGT | Higher hypertension risk | Meta-analysis |
| rs76767219 | — | GWAS association (p=1.0e-09) | Meta-analysis |
| rs12423664 | — | GWAS association (p=3.0e-10) | Meta-analysis |
| rs12509595 | — | GWAS association (p=1.0e-88) | Major Consortium Study |
| rs3918226 | NOS3 | GWAS association (p=5.0e-52) | Major Consortium Study |
| rs12978472 | — | GWAS association (p=3.0e-48) | Major Consortium Study |
| rs604723 | ARHGAP42 | GWAS association (p=9.0e-48) | Major Consortium Study |
| rs45603435 | — | GWAS association (p=2.0e-43) | Major Consortium Study |
| rs62048402 | FTO | GWAS association (p=2.0e-42) | Major Consortium Study |
| rs7310615 | SH2B3 | GWAS association (p=3.0e-38) | Major Consortium Study |
| rs569550 | — | GWAS association (p=3.0e-32) | Major Consortium Study |
| rs1275978 | KCNK3 | GWAS association (p=3.0e-28) | Major Consortium Study |
| rs4766578 | ATXN2 | GWAS association (p=8.0e-28) | Major Consortium Study |
| rs1801253 | ADRB1 | GWAS association (p=6.0e-27) | Major Consortium Study |
| rs45553335 | — | GWAS association (p=9.0e-27) | Major Consortium Study |
| rs2455569 | — | GWAS association (p=9.0e-27) | Major Consortium Study |
| rs148411205 | — | GWAS association (p=1.0e-26) | Major Consortium Study |
| rs77431689 | INSR | GWAS association (p=3.0e-26) | Major Consortium Study |
| rs11105375 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs2392929 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs12656497 | — | GWAS association (p=1.0e-24) | Major Consortium Study |
| rs13154066 | — | GWAS association (p=4.0e-24) | Major Consortium Study |
| rs60772526 | HOTTIP | GWAS association (p=6.0e-24) | Major Consortium Study |
| rs2023843 | — | GWAS association (p=9.0e-24) | Major Consortium Study |
| rs2493136 | AGT | GWAS association (p=5.0e-23) | Major Consortium Study |
| rs1234988 | ARHGAP42 | GWAS association (p=5.0e-22) | Major Consortium Study |
| rs11191548 | CNNM2 | GWAS association (p=7.0e-22) | Major Consortium Study |
| rs3821843 | — | GWAS association (p=1.0e-20) | Major Consortium Study |
| rs1214759 | — | GWAS association (p=2.0e-20) | Major Consortium Study |
| rs56388530 | — | GWAS association (p=3.0e-20) | Major Consortium Study |
| rs117778193 | — | GWAS association (p=2.0e-19) | Major Consortium Study |
| rs35973496 | — | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs10774625 | ATXN2 | GWAS association (p=4.0e-19) | Major Consortium Study |
| rs13028310 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs3796592 | — | GWAS association (p=1.0e-18) | Major Consortium Study |
| rs2306363 | — | GWAS association (p=2.0e-18) | Major Consortium Study |
| rs4932372 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs4932179 | — | GWAS association (p=3.0e-18) | Major Consortium Study |
| rs4470517 | — | GWAS association (p=4.0e-18) | Major Consortium Study |
| rs12222581 | — | GWAS association (p=4.0e-18) | Major Consortium Study |
| rs73306860 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs74181299 | CEP68 | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs8078510 | — | GWAS association (p=1.0e-17) | Major Consortium Study |
| rs17608766 | GOSR2 | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs9603374 | — | GWAS association (p=2.0e-17) | Major Consortium Study |
| rs57541197 | — | GWAS association (p=7.0e-17) | Major Consortium Study |
Showing the top 100 of 405 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.