HOXA3
homeobox A3
Summary
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Known Variants40 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs763446165 | 7:27,147,556 | G/A | — | uncertain significance |
| rs1289116241 | 7:27,147,572 | C/G | — | uncertain significance |
| rs757934192 | 7:27,147,604 | T/C | — | uncertain significance |
| rs2534533110 | 7:27,147,608 | T/C | — | uncertain significance |
| rs780452042 | 7:27,147,618 | C/G | — | uncertain significance |
| rs371131962 | 7:27,147,623 | C/T | — | uncertain significance |
| rs771076275 | 7:27,147,700 | G/C | — | uncertain significance |
| rs778107219 | 7:27,147,746 | G/T | — | uncertain significance |
| rs2534535189 | 7:27,147,754 | T/A | — | uncertain significance |
| rs775867530 | 7:27,147,773 | C/A | — | uncertain significance |
| rs781409624 | 7:27,147,827 | G/A | — | uncertain significance |
| rs774237769 | 7:27,147,854 | C/A | — | uncertain significance |
| rs1455226009 | 7:27,147,912 | G/C | — | uncertain significance |
| rs1279020607 | 7:27,147,929 | G/T | — | uncertain significance |
| rs565794030 | 7:27,147,956 | T/C | — | likely benign |
| rs138670627 | 7:27,148,042 | C/T | — | uncertain significance |
| rs141075773 | 7:27,148,057 | G/T | — | uncertain significance |
| rs576449568 | 7:27,148,084 | C/T | — | uncertain significance |
| rs146963463 | 7:27,148,190 | T/C | — | uncertain significance |
| rs777176111 | 7:27,148,229 | T/G | — | uncertain significance |
| rs137977036 | 7:27,148,234 | T/A | — | uncertain significance |
| rs144351903 | 7:27,148,297 | G/C | — | uncertain significance |
| rs1338817885 | 7:27,149,815 | G/A | — | uncertain significance |
| rs375062129 | 7:27,149,830 | G/A | — | uncertain significance |
| rs769208429 | 7:27,149,841 | G/A | — | uncertain significance |
| rs777978952 | 7:27,149,928 | G/A | — | uncertain significance |
| rs1438047631 | 7:27,149,939 | G/T | — | likely benign |
| rs1784291558 | 7:27,149,955 | G/A | — | uncertain significance |
| rs1784291781 | 7:27,149,956 | G/A | — | uncertain significance |
| rs1038708524 | 7:27,149,997 | G/T | — | uncertain significance |
| rs2534553017 | 7:27,150,004 | C/T | — | uncertain significance |
| rs2534553175 | 7:27,150,018 | T/C | — | uncertain significance |
| rs2534553970 | 7:27,150,084 | C/T | — | uncertain significance |
| rs146381041 | 7:27,150,133 | C/T | — | uncertain significance |
| rs746085776 | 7:27,150,150 | G/A | — | likely benign |
| rs6969780 | 7:27,159,136 | G/C | — | benign |
| rs17471520 | 7:27,178,790 | T/G | — | — |
| rs3735528 | 7:27,183,468 | G/T | regulatory region variant | — |
| rs4265096 | 7:27,185,070 | T/G | — | — |
| rs62454420 | 7:27,191,804 | A/C | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.