ARHGAP31

Rho GTPase activating protein 31

Summary

This gene encodes a GTPase-activating protein (GAP). A variety of cellular processes are regulated by Rho GTPases which cycle between an inactive form bound to GDP and an active form bound to GTP. This cycling between inactive and active forms is regulated by guanine nucleotide exchange factors and GAPs. The encoded protein is a GAP shown to regulate two GTPases involved in protein trafficking and cell growth. [provided by RefSeq, Jul 2008]

Known Variants440 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs4687994	3:119,013,558	G/A	—	benign
rs62265186	3:119,013,603	G/A	—	likely benign
rs72960626	3:119,013,714	A/C	—	benign
rs1431881272	3:119,013,770	A/G	—	uncertain significance
rs1227931818	3:119,013,780	T/C	—	uncertain significance
rs1040286577	3:119,013,804	C/T	—	uncertain significance
rs2079520306	3:119,013,850	T/C	—	uncertain significance
rs76783588	3:119,013,860	C/T	—	likely benign
rs3732412	3:119,013,928	A/T	—	benign
rs79691701	3:119,014,034	T/C	—	likely benign
rs78184961	3:119,014,135	G/C	—	likely benign
rs112869065	3:119,022,636	G/T	—	—
rs10934490	3:119,030,960	A/G	regulatory region variant	—
rs9861688	3:119,036,843	G/T	intron variant	—
rs186943264	3:119,043,459	G/C	upstream gene variant	—
rs10934491	3:119,068,312	A/C	regulatory region variant	—
rs6438524	3:119,083,833	C/T	—	benign
rs143737497	3:119,083,869	A/G	—	benign
rs116187120	3:119,084,114	G/A	—	benign
rs113568026	3:119,084,126	C/A	—	benign
rs772308862	3:119,084,147	C/G	—	likely benign
rs2472814560	3:119,084,154	T/C	—	likely benign
rs1559980914	3:119,084,159	A/G	—	likely benign
rs2080244449	3:119,084,178	A/G	—	uncertain significance
rs1483053797	3:119,084,195	A/G	—	uncertain significance
rs2080244695	3:119,084,204	C/T	—	uncertain significance
rs2107622807	3:119,084,207	G/A	—	uncertain significance
rs781190136	3:119,084,209	C/T	—	likely benign
rs375072197	3:119,084,212	C/T	—	likely benign
rs141911639	3:119,084,271	C/T	—	benign
rs543552697	3:119,084,274	A/C	—	likely benign
rs17203055	3:119,084,331	A/G	intron variant	benign
rs115297448	3:119,084,334	G/A	—	likely benign
rs138832644	3:119,084,547	C/T	—	likely benign
rs2080267192	3:119,087,199	C/G	—	likely benign
rs2080267293	3:119,087,201	C/T	—	likely benign
rs779874581	3:119,087,202	C/T	—	likely benign
rs369076345	3:119,087,203	G/A	—	likely benign
rs747038976	3:119,087,238	C/A	—	uncertain significance
rs142578368	3:119,087,240	A/G	—	likely benign
rs2080267866	3:119,087,265	T/C	—	uncertain significance
rs1289473407	3:119,087,294	G/A	—	likely benign
rs754843424	3:119,087,333	C/T	—	likely benign
rs756581922	3:119,087,362	C/T	—	uncertain significance
rs200619820	3:119,087,382	A/G	—	likely benign
rs2318370	3:119,099,598	G/A	—	benign
rs79225620	3:119,099,638	C/T	—	benign
rs765104598	3:119,099,739	T/C	—	likely benign
rs200397968	3:119,099,744	T/G	—	likely benign
rs2472831069	3:119,099,750	G/A	—	uncertain significance
rs763491256	3:119,099,761	C/T	—	uncertain significance
rs750455296	3:119,099,762	G/T	—	likely benign
rs2080391088	3:119,099,764	A/G	—	uncertain significance
rs202229113	3:119,099,767	G/A	—	uncertain significance
rs150339878	3:119,099,786	G/C	—	likely benign
rs201216830	3:119,099,791	G/A	—	conflicting classifications of pathogenicity
rs759535946	3:119,099,798	A/G	—	likely benign
rs374718588	3:119,099,812	A/C	—	uncertain significance
rs79505114	3:119,100,023	G/A	—	likely benign
rs72966428	3:119,100,089	A/G	—	likely benign
rs868590646	3:119,100,842	A/G	—	likely benign
rs115561893	3:119,100,902	T/G	—	benign
rs73187863	3:119,101,039	T/A	—	benign
rs2107631521	3:119,101,126	C/A	—	likely benign
rs10049221	3:119,101,132	G/A	—	likely benign
rs201927115	3:119,101,142	C/G	—	conflicting classifications of pathogenicity
rs201519981	3:119,101,159	G/A	—	conflicting classifications of pathogenicity
rs781008921	3:119,101,168	C/T	—	uncertain significance
rs1449325748	3:119,101,173	A/G	—	uncertain significance
rs1490333740	3:119,101,179	T/A	—	uncertain significance
rs774009946	3:119,101,189	G/C	—	conflicting classifications of pathogenicity
rs139733647	3:119,101,206	G/A	—	conflicting classifications of pathogenicity
rs1304654063	3:119,101,232	G/T	—	likely benign
rs565728106	3:119,101,245	A/T	—	likely benign
rs374706861	3:119,101,257	T/C	—	likely benign
rs748893560	3:119,101,264	C/A	—	likely benign
rs116095203	3:119,101,611	T/C	—	likely benign
rs114597100	3:119,101,761	G/A	—	likely benign
rs369993733	3:119,101,918	T/C	—	likely benign
rs16829782	3:119,101,925	T/C	—	benign
rs1183202197	3:119,101,926	G/A	—	uncertain significance
rs539898181	3:119,101,927	G/T	—	benign
rs199650901	3:119,101,950	A/C	—	uncertain significance
rs376381685	3:119,101,958	C/G	—	uncertain significance
rs2080416784	3:119,101,973	C/T	—	likely benign
rs2472834982	3:119,101,980	G/A	—	uncertain significance
rs768829713	3:119,101,987	G/A	—	uncertain significance
rs774626312	3:119,101,989	G/A	—	uncertain significance
rs2472835020	3:119,101,992	C/T	—	uncertain significance
rs368795933	3:119,102,005	T/C	—	uncertain significance
rs1359689323	3:119,102,009	G/A	—	likely benign
rs1239955501	3:119,102,013	A/G	—	uncertain significance
rs761116153	3:119,102,016	T/C	—	likely benign
rs764713087	3:119,102,024	T/C	—	likely benign
rs1010784829	3:119,102,030	T/C	—	likely benign
rs145326425	3:119,102,045	C/T	—	benign
rs2080418229	3:119,102,050	C/T	—	uncertain significance
rs751793	3:119,102,053	C/T	—	likely benign
rs202118332	3:119,102,067	A/C	—	uncertain significance
rs2472835193	3:119,102,073	G/A	—	uncertain significance

Showing 100 of 440 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.