Trait

SNPs associated with Systemic Lupus Erythematosus

668 genetic variants across 160 genes have been associated with Systemic Lupus Erythematosus in published research. Key genes include AFF1, AFF3, AIF1.

Associated variants668 total

rsidGeneEffectEvidence
rs117026326GTF2IGWAS association (p=2.0e-298)Meta-analysis
rs7800325—GWAS association (p=1.0e-280)Meta-analysis
rs199789198NCF1GWAS association (p=3.0e-194)Meta-analysis
rs11889341STAT4GWAS association (p=5.0e-123)Meta-analysis
rs9268807—GWAS association (p=5.0e-117)Meta-analysis
rs2205960TNFSF4GWAS association (p=3.0e-32)Meta-analysis
rs13277113—GWAS association (p=1.0e-10)Meta-analysis
rs9494894—GWAS association (p=3.0e-84)Meta-analysis
rs3757387—GWAS association (p=9.0e-79)Meta-analysis
rs28359827—GWAS association (p=2.0e-71)Meta-analysis
rs2736332—GWAS association (p=2.0e-70)Meta-analysis
rs34723256—GWAS association (p=4.0e-68)Meta-analysis
rs143176121GTF2IGWAS association (p=2.0e-66)Meta-analysis
rs587680541—GWAS association (p=4.0e-62)Meta-analysis
rs77009341HIP1GWAS association (p=6.0e-62)Meta-analysis
rs62447171—GWAS association (p=9.0e-60)Meta-analysis
rs11501246—GWAS association (p=2.0e-58)Meta-analysis
rs729302—GWAS association (p=6.0e-57)Meta-analysis
rs9273190HLA-DQA1GWAS association (p=1.0e-54)Meta-analysis
rs1059702IRAK1GWAS association (p=6.0e-54)Meta-analysis
rs117278480TNFSF4GWAS association (p=2.0e-52)Meta-analysis
rs71403211—GWAS association (p=3.0e-49)Meta-analysis
rs2516465LINC01149GWAS association (p=6.0e-48)Meta-analysis
rs9269207—GWAS association (p=6.0e-48)Meta-analysis
rs10036748TNIP1GWAS association (p=2.0e-09)Meta-analysis
rs5754344UBE2L3GWAS association (p=2.0e-45)Meta-analysis
rs41298401IRF5GWAS association (p=5.0e-45)Meta-analysis
rs4251697CDKN1BGWAS association (p=1.0e-43)Meta-analysis
rs7753017—GWAS association (p=5.0e-43)Meta-analysis
rs7574865STAT4GWAS association (p=5.0e-42)Meta-analysis
rs7097397WDFY4GWAS association (p=8.0e-12)Meta-analysis
rs3135461—GWAS association (p=2.0e-39)Meta-analysis
rs548234—GWAS association (p=5.0e-12)Meta-analysis
rs2039982—GWAS association (p=2.0e-37)Meta-analysis
rs542914466AIF1GWAS association (p=2.0e-37)Meta-analysis
rs2431697—GWAS association (p=3.0e-37)Meta-analysis
rs36030018—GWAS association (p=3.0e-36)Meta-analysis
rs13385731RASGRP3GWAS association (p=1.0e-15)Meta-analysis
rs11117432LOC124903741GWAS association (p=1.0e-32)Meta-analysis
rs78724056TNPO3GWAS association (p=2.0e-32)Meta-analysis
rs34452045—GWAS association (p=3.0e-31)Meta-analysis
rs9274384HLA-DQB1GWAS association (p=5.0e-31)Meta-analysis
rs10845602—GWAS association (p=6.0e-31)Meta-analysis
rs1966002—GWAS association (p=8.0e-31)Meta-analysis
rs76107698FCGR2CGWAS association (p=2.0e-30)Meta-analysis
rs144104218—GWAS association (p=2.0e-30)Meta-analysis
rs534723171HLA-AGWAS association (p=2.0e-30)Meta-analysis
rs11059928SLC15A4GWAS association (p=2.0e-30)Meta-analysis
rs2819426—GWAS association (p=3.0e-30)Meta-analysis
rs113720465CYP21A2GWAS association (p=6.0e-30)Meta-analysis
rs2254546—GWAS association (p=4.0e-28)Meta-analysis
rs447632—GWAS association (p=7.0e-28)Meta-analysis
rs112262437—GWAS association (p=2.0e-27)Meta-analysis
rs9268486BTNL2GWAS association (p=8.0e-27)Meta-analysis
rs794368—GWAS association (p=2.0e-26)Meta-analysis
rs9270970—GWAS association (p=4.0e-26)Meta-analysis
rs10896045—GWAS association (p=7.0e-26)Meta-analysis
rs6590330LOC124902789GWAS association (p=2.0e-25)Meta-analysis
rs2256974—GWAS association (p=2.0e-25)Meta-analysis
rs10239000—GWAS association (p=2.0e-25)Meta-analysis
rs6641111PRPS2GWAS association (p=3.0e-25)Meta-analysis
rs4948496ARID5BGWAS association (p=2.0e-24)Meta-analysis
rs4643809—GWAS association (p=4.0e-24)Meta-analysis
rs9270984—GWAS association (p=5.0e-24)Meta-analysis
rs75163761WAKMAR2GWAS association (p=5.0e-24)Meta-analysis
rs200283861C4BGWAS association (p=3.0e-23)Meta-analysis
rs574027387—GWAS association (p=3.0e-23)Meta-analysis
rs77971648FCHSD2GWAS association (p=3.0e-23)Meta-analysis
rs79171842GTF2IGWAS association (p=3.0e-23)Meta-analysis
rs1431403HLA-DPA1GWAS association (p=1.0e-22)Meta-analysis
rs6457796—GWAS association (p=3.0e-22)Meta-analysis
rs1143679ITGAMHigher lupus riskMeta-analysis
rs57141708ELF1GWAS association (p=7.0e-22)Meta-analysis
rs113523948—GWAS association (p=3.0e-21)Meta-analysis
rs2647078—GWAS association (p=9.0e-21)Meta-analysis
rs7579944—GWAS association (p=1.0e-20)Meta-analysis
rs2732540—GWAS association (p=1.0e-20)Meta-analysis
rs13244581—GWAS association (p=2.0e-20)Meta-analysis
rs2263318HCP5GWAS association (p=1.0e-19)Meta-analysis
rs111508444—GWAS association (p=2.0e-19)Meta-analysis
rs77285596ZSCAN23GWAS association (p=2.0e-19)Meta-analysis
rs480958—GWAS association (p=3.0e-19)Meta-analysis
rs368529276TSBP1GWAS association (p=4.0e-19)Meta-analysis
rs140780894—GWAS association (p=4.0e-19)Meta-analysis
rs111743557—GWAS association (p=2.0e-18)Meta-analysis
rs4801882—GWAS association (p=2.0e-18)Meta-analysis
rs75460055—GWAS association (p=5.0e-18)Meta-analysis
rs530634980GTF2IRD1GWAS association (p=5.0e-18)Meta-analysis
rs77465633ATXN2GWAS association (p=7.0e-18)Meta-analysis
rs116352702—GWAS association (p=8.0e-18)Meta-analysis
rs2230926TNFAIP3GWAS association (p=1.0e-17)Meta-analysis
rs28364822TNPO3GWAS association (p=1.0e-17)Meta-analysis
rs34361002—GWAS association (p=1.0e-17)Meta-analysis
rs11032994LOC105376627GWAS association (p=1.0e-17)Meta-analysis
rs7725218TERTGWAS association (p=2.0e-17)Meta-analysis
rs77885959GTF2H1GWAS association (p=3.0e-17)Meta-analysis
rs10845606GPR19GWAS association (p=4.0e-17)Meta-analysis
rs6705628DGUOK-AS1GWAS association (p=7.0e-17)Meta-analysis
rs113284964—GWAS association (p=1.0e-16)Meta-analysis
rs55882956TYK2GWAS association (p=1.0e-16)Meta-analysis

Showing the top 100 of 668 variants by evidence strength.

Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.