rs10896045
▶GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (9)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
glutaminyl-peptide cyclotransferase measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.13
p 5.0e-119
N 47,745
Large GWAS
European
Pietzner M et al. “Mapping the proteo-genomic convergence of human diseases.” Science (new York, N.y.) 374(6569):eabj1541 (2021)
Allele G
OR 0.15
p 5.0e-26
N 10,708
Large GWAS
European
systemic lupus erythematosus
Yin X et al. “Meta-analysis of 208370 East Asians identifies 113 susceptibility loci for systemic lupus erythematosus.” Annals of the Rheumatic Diseases 80(5):632-640 (2021)
Allele A
OR 1.17
p 7.0e-26
N 208,370
Meta-analysisLarge GWAS
East Asian
blood protein amount
Gudjonsson A et al. “A genome-wide association study of serum proteins reveals shared loci with common diseases.” Nature Communications 13(1):480 (2022)
Allele A
OR 0.17
p 2.0e-17
N 5,360
Large GWAS
European
interleukin-5 receptor subunit alpha measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 2.0e-16
N 47,745
Large GWAS
European
IGA glomerulonephritis
Kiryluk K et al. “Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy.” Nature Genetics 55(7):1091-1105 (2023)
Allele A
OR 1.18
p 5.0e-13
N 25,852
Large GWAS
multi-ancestry
level of immunoglobulin lambda constant 2 (human) in blood
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.04
p 4.0e-12
N 47,745
Large GWAS
European
intercellular adhesion molecule 3 measurement
Loya H et al. “A scalable variational inference approach for increased mixed-model association power.” Nature Genetics 57(2):461-468 (2025)
Allele G
OR 0.03
p 1.0e-11
N 47,745
Large GWAS
European
protein shisa-3 homolog measurement
Allele G
OR —
β 0.180
p 1.0e-11
N 3,301
Large GWAS
European
atopic eczema
Chen Y et al. “Genome-Wide Integration of Genetic and Genomic Studies of Atopic Dermatitis: Insights into Genetic Architecture and Pathogenesis.” The Journal of Investigative Dermatology 142(11):2958-2967.e8 (2022)
Allele A
OR 0.06
p 8.0e-9
N 837,496
Large GWAS
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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