FCGR2C
Fc gamma receptor IIc (gene/pseudogene)
Summary
This gene encodes one of three members of a family of low-affinity immunoglobulin gamma Fc receptors found on the surface of many immune response cells. The encoded protein is a transmembrane glycoprotein and may be involved in phagocytosis and clearing of immune complexes. An allelic polymorphism in this gene results in both coding and non-coding variants. [provided by RefSeq, Apr 2012]
Known Variants40 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs527665651 | 1:161,555,469 | G/A | — | — |
| rs114945036 | 1:161,559,256 | C/T | intron variant | — |
| rs3933769 | 1:161,559,327 | A/G | regulatory region variant | — |
| rs777701374 | 1:161,559,360 | C/A | — | uncertain significance |
| rs200616774 | 1:161,559,361 | C/T | — | uncertain significance |
| rs201231731 | 1:161,559,384 | C/G | — | uncertain significance |
| rs754528757 | 1:161,559,455 | C/G | — | uncertain significance |
| rs111603147 | 1:161,559,466 | C/A | — | likely benign |
| rs187810534 | 1:161,559,502 | C/T | — | uncertain significance |
| rs754724878 | 1:161,559,543 | G/A | — | uncertain significance |
| rs138747765 | 1:161,559,571 | C/T | missense variant | — |
| rs1488918202 | 1:161,559,576 | C/T | — | uncertain significance |
| rs78603008 | 1:161,559,720 | G/A | regulatory region variant | — |
| rs779183591 | 1:161,560,985 | T/A | — | uncertain significance |
| rs375060379 | 1:161,560,987 | G/A | — | likely benign |
| rs569144897 | 1:161,561,005 | T/C | — | uncertain significance |
| rs2102561211 | 1:161,561,011 | G/T | — | uncertain significance |
| rs376800866 | 1:161,561,068 | C/T | — | uncertain significance |
| rs750538292 | 1:161,561,072 | C/T | — | likely benign |
| rs552737498 | 1:161,561,081 | A/C | — | uncertain significance |
| rs573371878 | 1:161,561,092 | C/T | — | uncertain significance |
| rs201968350 | 1:161,561,150 | C/T | — | uncertain significance |
| rs777399731 | 1:161,561,180 | C/A | — | uncertain significance |
| rs373013207 | 1:161,562,113 | C/G | — | — |
| rs61801820 | 1:161,564,153 | C/G | upstream gene variant | — |
| rs115987345 | 1:161,564,392 | T/C | upstream gene variant | — |
| rs71519209 | 1:161,564,606 | C/T | upstream gene variant | — |
| rs1678606777 | 1:161,565,343 | C/G | — | uncertain significance |
| rs2527110039 | 1:161,565,351 | A/C | — | uncertain significance |
| rs367710761 | 1:161,565,352 | C/G | — | uncertain significance |
| rs114010589 | 1:161,565,408 | T/C | missense variant | — |
| rs61801823 | 1:161,565,958 | A/C | — | — |
| rs181468352 | 1:161,567,036 | A/G | intron variant | — |
| rs61801824 | 1:161,567,067 | T/A | intron variant | — |
| rs759044158 | 1:161,569,430 | G/A | — | uncertain significance |
| rs1199157544 | 1:161,569,534 | G/A | — | uncertain significance |
| rs138731942 | 1:161,569,569 | C/T | intron variant | — |
| rs1678700094 | 1:161,569,573 | C/G | — | uncertain significance |
| rs76107698 | 1:161,569,829 | G/C | intron variant | — |
| rs537891035 | 1:161,570,407 | T/G | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.