ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Summary
This gene encodes a member of the glycosyltransferase 29 family, a group of enzymes involved in protein glycosylation. The encoded protein is targeted to Golgi membranes but may be proteolytically processed and secreted. The gene product may also be involved in the increased expression of sialyl Lewis X antigen seen in inflammatory responses. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Known Variants47 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs192594750 | 11:126,225,426 | G/A | regulatory region variant | — |
| rs73632737 | 11:126,226,775 | G/C | regulatory region variant | — |
| rs181897168 | 11:126,227,095 | G/A | regulatory region variant | — |
| rs59379014 | 11:126,228,000 | C/T | regulatory region variant | — |
| rs73632745 | 11:126,229,617 | C/T | regulatory region variant | — |
| rs78689694 | 11:126,234,820 | G/A | — | — |
| rs630149 | 11:126,235,082 | C/G | — | — |
| rs36046161 | 11:126,235,513 | T/A | intron variant | — |
| rs74612335 | 11:126,238,633 | T/A | — | — |
| rs60843925 | 11:126,238,832 | T/C | — | — |
| rs10893498 | 11:126,241,696 | G/A | intron variant | — |
| rs9704688 | 11:126,242,372 | C/T | intron variant | — |
| rs11220462 | 11:126,243,952 | G/A | intron variant | — |
| rs73021419 | 11:126,250,647 | C/T | intron variant | — |
| rs10893501 | 11:126,251,033 | A/G | intron variant | — |
| rs2066985 | 11:126,251,286 | G/C | — | — |
| rs67358277 | 11:126,251,650 | A/G | — | — |
| rs73021423 | 11:126,253,641 | T/C | intron variant | — |
| rs11220464 | 11:126,253,877 | C/T | intron variant | — |
| rs11220465 | 11:126,257,779 | G/A | intron variant | — |
| rs4390359 | 11:126,260,715 | C/T | intron variant | — |
| rs12290068 | 11:126,261,564 | G/A | intron variant | — |
| rs2186717 | 11:126,261,832 | G/T | — | — |
| rs7928391 | 11:126,262,616 | C/G | — | — |
| rs11220471 | 11:126,266,665 | A/G | intron variant | — |
| rs10893506 | 11:126,275,960 | T/A | regulatory region variant | — |
| rs190884962 | 11:126,276,006 | C/T | regulatory region variant | — |
| rs148736743 | 11:126,276,394 | C/G | — | uncertain significance |
| rs146779997 | 11:126,276,431 | G/A | — | uncertain significance |
| rs758640915 | 11:126,276,846 | T/C | — | uncertain significance |
| rs201196480 | 11:126,276,857 | G/A | — | uncertain significance |
| rs144143100 | 11:126,276,870 | C/T | — | uncertain significance |
| rs371057579 | 11:126,277,155 | G/A | — | uncertain significance |
| rs1344403853 | 11:126,277,199 | A/G | — | uncertain significance |
| rs751179970 | 11:126,277,203 | C/T | — | uncertain significance |
| rs2230278 | 11:126,277,216 | C/T | — | benign |
| rs768237243 | 11:126,278,007 | C/T | — | uncertain significance |
| rs754122705 | 11:126,278,041 | G/A | — | uncertain significance |
| rs2230279 | 11:126,278,075 | C/T | — | benign |
| rs2298475 | 11:126,278,203 | C/T | — | benign |
| rs865787980 | 11:126,278,362 | A/G | — | uncertain significance |
| rs758506923 | 11:126,279,209 | A/G | — | uncertain significance |
| rs1316361 | 11:126,279,365 | A/C | — | — |
| rs3781780 | 11:126,280,544 | G/T | intron variant | — |
| rs4937126 | 11:126,281,897 | G/A | regulatory region variant | — |
| rs2236653 | 11:126,283,785 | C/T | intron variant | — |
| rs113839370 | 11:126,284,439 | G/A | — | — |
Gene information from NCBI Gene. Variant classifications from ClinVar.