Trait
SNPs associated with Low Density Lipoprotein Cholesterol Measurement
3191 genetic variants across 567 genes have been associated with Low Density Lipoprotein Cholesterol Measurement in published research. Key genes include A1CF, ABCA1, ABCA4.
Associated variants3,191 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs12740374 | CELSR2 | GWAS association (p=2.0e-42) | Meta-analysis |
| rs7412 | APOE | GWAS association (p=0.0e+00) | Meta-analysis |
| rs28362286 | PCSK9 | GWAS association (p=0.0e+00) | Meta-analysis |
| rs73015020 | — | GWAS association (p=8.0e-45) | Meta-analysis |
| rs35143646 | ARSL | GWAS association (p=2.0e-25) | Meta-analysis |
| rs1050828 | G6PD | GWAS association (p=1.0e-18) | Meta-analysis |
| rs2230488 | RPS6KA3 | GWAS association (p=3.0e-16) | Meta-analysis |
| rs1802288 | TSPAN6 | GWAS association (p=7.0e-16) | Meta-analysis |
| rs143375141 | — | GWAS association (p=8.0e-13) | Meta-analysis |
| rs4788609 | PMFBP1 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs114810281 | ZGLP1 | GWAS association (p=1.0e-09) | Meta-analysis |
| rs6845395 | FHIP1A | GWAS association (p=3.0e-09) | Meta-analysis |
| rs4791641 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs2238675 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs9784624 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs2435386 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs141822553 | — | GWAS association (p=3.0e-08) | Meta-analysis |
| rs35804417 | GATB | GWAS association (p=4.0e-08) | Meta-analysis |
| rs660240 | CELSR2 | GWAS association (p=1.0e-26) | Meta-analysis |
| rs13392272 | — | GWAS association (p=3.0e-95) | Meta-analysis |
| rs75143493 | LOC124901454 | GWAS association (p=6.0e-10) | Meta-analysis |
| rs7055206 | — | GWAS association (p=5.0e-139) | Meta-analysis |
| rs12916 | HMGCR | GWAS association (p=5.0e-45) | Major Consortium Study |
| rs6511720 | LDLR | GWAS association (p=4.0e-117) | Major Consortium Study |
| rs11591147 | PCSK9 | GWAS association (p=2.0e-44) | Major Consortium Study |
| rs4299376 | ABCG8 | GWAS association (p=2.0e-47) | Major Consortium Study |
| rs4420638 | APOC1 | GWAS association (p=9.0e-147) | Major Consortium Study |
| rs143020224 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs62117160 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs28399654 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs365653 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs6859 | NECTIN2 | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs142042446 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs7254892 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs34095326 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs11668327 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs769449 | APOE | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs141622900 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs7259004 | APOC1P1 | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs12721109 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs1065853 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs28601761 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs73015024 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs312976 | — | GWAS association (p=4.9e-324) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs611917 | CELSR2 | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs144826254 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs140480140 | APOC1 | GWAS association (p=4.0e-323) | Major Consortium Study |
| rs10455872 | LPA | GWAS association (p=3.0e-321) | Major Consortium Study |
| rs2335418 | — | GWAS association (p=5.0e-321) | Major Consortium Study |
| rs964184 | APOA5 | GWAS association (p=1.0e-26) | Major Consortium Study |
| rs28399637 | — | GWAS association (p=1.0e-314) | Major Consortium Study |
| rs35271870 | — | GWAS association (p=8.0e-304) | Major Consortium Study |
| rs2519093 | ABO | GWAS association (p=2.0e-303) | Major Consortium Study |
| rs58542926 | TM6SF2 | GWAS association (p=3.0e-291) | Major Consortium Study |
| rs12151108 | — | GWAS association (p=1.0e-262) | Major Consortium Study |
| rs72658867 | LDLR | GWAS association (p=7.0e-239) | Major Consortium Study |
| rs577584 | LOC124905593 | GWAS association (p=1.0e-229) | Major Consortium Study |
| rs60049679 | — | GWAS association (p=3.0e-217) | Major Consortium Study |
| rs77542162 | ABCA6 | GWAS association (p=1.0e-212) | Major Consortium Study |
| rs71352239 | — | GWAS association (p=4.0e-211) | Major Consortium Study |
| rs76366838 | — | GWAS association (p=1.0e-207) | Major Consortium Study |
| rs10166144 | — | GWAS association (p=9.0e-195) | Major Consortium Study |
| rs74617384 | — | GWAS association (p=9.0e-193) | Major Consortium Study |
| rs41289512 | — | GWAS association (p=2.0e-188) | Major Consortium Study |
| rs34042070 | — | GWAS association (p=1.0e-177) | Major Consortium Study |
| rs1883711 | — | GWAS association (p=4.0e-171) | Major Consortium Study |
| rs6511721 | — | GWAS association (p=1.0e-166) | Major Consortium Study |
| rs2954038 | — | GWAS association (p=1.0e-165) | Major Consortium Study |
| rs62116778 | — | GWAS association (p=1.0e-164) | Major Consortium Study |
| rs507666 | ABO | GWAS association (p=1.0e-157) | Major Consortium Study |
| rs533617 | APOB | GWAS association (p=1.0e-155) | Major Consortium Study |
| rs12052058 | — | GWAS association (p=1.0e-155) | Major Consortium Study |
| rs17216525 | — | GWAS association (p=2.0e-152) | Major Consortium Study |
| rs2199575 | — | GWAS association (p=6.0e-149) | Major Consortium Study |
| rs73013159 | — | GWAS association (p=6.0e-147) | Major Consortium Study |
| rs6698843 | CELSR2 | GWAS association (p=1.0e-139) | Major Consortium Study |
| rs12691088 | — | GWAS association (p=3.0e-137) | Major Consortium Study |
| rs7188 | — | GWAS association (p=1.0e-136) | Major Consortium Study |
| rs4970829 | — | GWAS association (p=3.0e-136) | Major Consortium Study |
| rs77960347 | LIPG | GWAS association (p=2.0e-132) | Major Consortium Study |
| rs550619 | — | GWAS association (p=2.0e-132) | Major Consortium Study |
| rs754340 | — | GWAS association (p=2.0e-131) | Major Consortium Study |
| rs585362 | — | GWAS association (p=8.0e-130) | Major Consortium Study |
| rs73015030 | — | GWAS association (p=7.0e-124) | Major Consortium Study |
| rs557933 | — | GWAS association (p=3.0e-120) | Major Consortium Study |
| rs2618566 | — | GWAS association (p=5.0e-117) | Major Consortium Study |
| rs55660224 | MYBPHL | GWAS association (p=3.0e-115) | Major Consortium Study |
| rs117310449 | — | GWAS association (p=2.0e-112) | Major Consortium Study |
| rs2000999 | HPR | GWAS association (p=2.0e-22) | Major Consortium Study |
| rs673548 | APOB | GWAS association (p=5.0e-112) | Major Consortium Study |
| rs2207132 | — | GWAS association (p=3.0e-108) | Major Consortium Study |
| rs780094 | GCKR | GWAS association (p=2.0e-105) | Major Consortium Study |
| rs11206510 | PCSK9 | GWAS association (p=4.0e-11) | Major Consortium Study |
| rs5942956 | TDGF1P3 | GWAS association (p=2.0e-102) | Major Consortium Study |
| rs144261139 | — | GWAS association (p=4.0e-102) | Major Consortium Study |
| rs12691202 | APOB | GWAS association (p=4.0e-99) | Major Consortium Study |
| rs1800961 | HNF4A | GWAS association (p=4.0e-98) | Major Consortium Study |
| rs9297994 | — | GWAS association (p=2.0e-97) | Major Consortium Study |
| rs2304130 | ZNF101 | GWAS association (p=6.0e-97) | Major Consortium Study |
Showing the top 100 of 3,191 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.