rs55660224
This variant is located in the MYBPHL gene.
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
apolipoprotein B measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.12
p 1.0e-163
N 354,097
Major Consortium StudyLarge GWAS
multi-ancestry
low density lipoprotein cholesterol measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.10
p 3.0e-115
N 355,197
Major Consortium StudyLarge GWAS
multi-ancestry
total cholesterol measurement
Sinnott-Armstrong N et al. “Genetics of 35 blood and urine biomarkers in the UK Biobank.” Nature Genetics 53(2):185-194 (2021)
Allele T
OR 0.09
p 6.0e-87
N 355,858
Major Consortium StudyLarge GWAS
multi-ancestry
cholesterol to total lipids in IDL percentage
Zoodsma M et al. “A genetic map of human metabolism across the allele frequency spectrum.” Nature Genetics 57(10):2445-2455 (2025)
Allele T
OR 0.02
p 6.0e-12
N 450,015
Large GWAS
multi-ancestry
▶ClinVar annotation
Benign★★★☆
3 submitters1 publicationnot provided; Familial pancreatic carcinoma; Malignant lymphoma, large B-cell, diffuse; Uterine carcinosarcoma; Nonpapillary renal cell carcinoma; Adrenocortical carcinoma, hereditary; Ovarian cancer; Colorectal cancer; Thymoma
View on ClinVar →About MYBPHL
This gene encodes a protein with two immunoglobulin superfamily domains and a fibronectin 3 domain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2012]
View all MYBPHL variants →Gene information from NCBI Gene. Variant classifications from ClinVar.
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