LIPG

lipase G, endothelial type

Summary

The protein encoded by this gene has substantial phospholipase activity and may be involved in lipoprotein metabolism and vascular biology. This protein is designated a member of the TG lipase family by its sequence and characteristic lid region which provides substrate specificity for enzymes of the TG lipase family. [provided by RefSeq, Jul 2008]

Known Variants136 total

rsid	Position (GRCh37)	Alleles	Class	ClinVar
rs9958947	18:47,086,932	C/T	upstream gene variant	—
rs3813082	18:47,088,043	A/G	—	—
rs34474737	18:47,088,655	T/G	regulatory region variant	—
rs199615862	18:47,088,678	G/T	—	likely benign
rs874565	18:47,088,690	C/A	—	benign
rs1444780892	18:47,088,714	C/T	—	likely benign
rs874566	18:47,088,741	C/T	—	benign
rs2084559894	18:47,088,747	A/C	—	likely benign
rs2511290762	18:47,088,748	C/T	—	uncertain significance
rs9963243	18:47,088,754	G/A	—	benign
rs761348318	18:47,088,789	G/A	—	likely benign
rs35978968	18:47,088,826	C/T	regulatory region variant	—
rs2511292669	18:47,091,700	A/C	—	uncertain significance
rs200103565	18:47,091,704	A/C	—	benign
rs2084591631	18:47,091,705	A/C	—	uncertain significance
rs767601561	18:47,091,722	G/A	—	uncertain significance
rs61761314	18:47,091,749	C/T	—	uncertain significance
rs2511292767	18:47,091,770	C/G	—	uncertain significance
rs554682739	18:47,091,793	C/T	—	likely benign
rs61729804	18:47,091,807	C/T	—	benign
rs2511292844	18:47,091,818	T/C	—	uncertain significance
rs745486229	18:47,091,860	G/A	—	uncertain significance
rs371455573	18:47,091,876	C/T	—	likely benign
rs201857867	18:47,093,796	C/G	—	benign
rs2084617440	18:47,093,814	G/T	—	uncertain significance
rs144341306	18:47,093,817	C/T	—	likely benign
rs774395060	18:47,093,823	C/T	—	likely benign
rs776866582	18:47,093,848	G/A	—	uncertain significance
rs1426284437	18:47,093,860	C/T	—	uncertain significance
rs2000813	18:47,093,864	C/T	missense variant	benign
rs201002261	18:47,093,866	A/G	—	uncertain significance
rs752816323	18:47,093,877	C/T	—	likely benign
rs111384586	18:47,093,878	G/A	—	uncertain significance
rs2084619274	18:47,093,882	A/G	—	uncertain significance
rs2148847897	18:47,093,887	G/A	—	uncertain significance
rs1388076492	18:47,093,892	G/A	—	likely benign
rs1307585859	18:47,093,976	G/A	—	uncertain significance
rs2097055	18:47,095,487	T/C	intron variant	—
rs545887569	18:47,095,791	T/C	—	benign
rs2511295502	18:47,095,805	A/G	—	uncertain significance
rs377474720	18:47,095,815	C/T	—	likely benign
rs772490746	18:47,095,827	C/T	—	likely benign
rs370118423	18:47,095,828	G/A	—	conflicting classifications of pathogenicity
rs2084640660	18:47,095,842	G/C	—	uncertain significance
rs889125342	18:47,095,846	G/A	—	uncertain significance
rs376166078	18:47,095,857	C/T	—	likely benign
rs139830474	18:47,095,866	C/T	—	likely benign
rs143163964	18:47,095,872	C/T	—	likely benign
rs562832653	18:47,095,881	A/G	—	likely benign
rs760086186	18:47,095,910	G/A	—	uncertain significance
rs1320700	18:47,096,016	G/A	regulatory region variant	—
rs74538801	18:47,097,575	T/C	intron variant	—
rs8094774	18:47,097,683	T/C	intron variant	—
rs368834078	18:47,101,729	T/C	—	uncertain significance
rs1369205373	18:47,101,735	G/T	—	likely benign
rs748825827	18:47,101,752	C/G	—	likely benign
rs768255956	18:47,101,770	G/A	—	likely benign
rs368016590	18:47,101,774	G/A	—	uncertain significance
rs199712385	18:47,101,796	C/T	—	uncertain significance
rs61762476	18:47,101,797	G/A	—	benign
rs35084417	18:47,101,836	G/T	—	likely benign
rs142545730	18:47,101,838	G/A	—	uncertain significance
rs578235397	18:47,101,845	C/T	—	likely benign
rs199744392	18:47,101,846	G/A	—	uncertain significance
rs2511299419	18:47,101,873	G/C	—	uncertain significance
rs1600552359	18:47,101,895	C/T	—	uncertain significance
rs767799856	18:47,101,932	C/T	—	likely benign
rs756583817	18:47,101,936	G/A	—	uncertain significance
rs2148850691	18:47,101,953	A/G	—	likely benign
rs59677798	18:47,104,324	G/T	—	—
rs34776160	18:47,107,769	T/C	—	benign
rs757992227	18:47,107,780	C/T	—	likely benign
rs777249823	18:47,107,781	C/T	—	likely benign
rs746455531	18:47,107,784	G/A	—	uncertain significance
rs1331901550	18:47,107,821	C/A	—	uncertain significance
rs138921240	18:47,107,823	G/A	—	uncertain significance
rs945256116	18:47,107,831	C/G	—	likely benign
rs753303386	18:47,107,857	A/G	—	uncertain significance
rs778182634	18:47,107,863	C/T	—	uncertain significance
rs61729805	18:47,107,884	C/T	—	conflicting classifications of pathogenicity
rs150193557	18:47,107,895	C/T	—	uncertain significance
rs747134984	18:47,107,911	T/C	—	uncertain significance
rs756805114	18:47,107,945	C/T	—	likely benign
rs749070239	18:47,107,975	C/A	—	uncertain significance
rs2511306292	18:47,108,719	G/T	—	likely benign
rs115921646	18:47,108,777	T/C	—	benign
rs1240317432	18:47,108,802	C/T	—	likely benign
rs201407808	18:47,108,803	G/A	—	uncertain significance
rs2511306401	18:47,108,832	C/G	—	likely benign
rs2511306431	18:47,108,852	T/C	—	uncertain significance
rs2511306433	18:47,108,854	T/C	—	uncertain significance
rs1342054673	18:47,108,863	C/T	—	likely benign
rs192969663	18:47,108,864	G/A	—	benign
rs1555778689	18:47,108,870	C/T	—	likely benign
rs117172986	18:47,109,189	C/T	intron variant	—
rs9951026	18:47,109,693	G/A	intron variant	—
rs374219453	18:47,109,922	G/C	—	benign
rs776284980	18:47,109,938	C/T	—	likely benign
rs138438163	18:47,109,939	G/A	—	likely benign
rs77960347	18:47,109,955	G/A	—	benign

Showing 100 of 136 variants. Use the SNP search for the full list.

Gene information from NCBI Gene. Variant classifications from ClinVar.