Trait
SNPs associated with High Density Lipoprotein Cholesterol Measurement
4133 genetic variants across 743 genes have been associated with High Density Lipoprotein Cholesterol Measurement in published research. Key genes include ABCA1, ABCA6, ABCA8.
Associated variants4,133 total
| rsid | Gene | Effect | Evidence |
|---|---|---|---|
| rs2070895 | LIPC | GWAS association (p=0.0e+00) | Meta-analysis |
| rs7499892 | CETP | GWAS association (p=1.0e-300) | Meta-analysis |
| rs2292318 | — | GWAS association (p=2.0e-126) | Meta-analysis |
| rs7412 | APOE | GWAS association (p=2.0e-106) | Meta-analysis |
| rs34065661 | CETP | GWAS association (p=8.0e-102) | Meta-analysis |
| rs2126263 | — | GWAS association (p=5.0e-39) | Meta-analysis |
| rs3744841 | — | GWAS association (p=4.0e-37) | Meta-analysis |
| rs5965342 | — | GWAS association (p=3.0e-25) | Meta-analysis |
| rs2070826 | FLNA | GWAS association (p=1.0e-22) | Meta-analysis |
| rs62603531 | — | GWAS association (p=7.0e-16) | Meta-analysis |
| rs5964416 | ZC3H12B | GWAS association (p=3.0e-12) | Meta-analysis |
| rs2472386 | — | GWAS association (p=1.0e-11) | Meta-analysis |
| rs6648533 | THOC2 | GWAS association (p=2.0e-11) | Meta-analysis |
| rs3289 | LPL | GWAS association (p=3.0e-11) | Meta-analysis |
| rs151113194 | CLIC2 | GWAS association (p=3.0e-11) | Meta-analysis |
| rs191084933 | — | GWAS association (p=7.0e-09) | Meta-analysis |
| rs884366 | — | GWAS association (p=1.0e-08) | Meta-analysis |
| rs60839105 | SEMA3C | GWAS association (p=1.0e-08) | Meta-analysis |
| rs7121538 | — | GWAS association (p=2.0e-08) | Meta-analysis |
| rs261334 | LIPC | GWAS association (p=5.0e-22) | Meta-analysis |
| rs28526159 | — | GWAS association (p=1.0e-42) | Meta-analysis |
| rs2367970 | — | GWAS association (p=9.0e-12) | Meta-analysis |
| rs77697917 | — | GWAS association (p=2.0e-42) | Meta-analysis |
| rs139120857 | FANCB | GWAS association (p=3.0e-79) | Meta-analysis |
| rs5934507 | — | GWAS association (p=8.0e-15) | Meta-analysis |
| rs7888119 | TXLNG | GWAS association (p=3.0e-17) | Meta-analysis |
| rs9989419 | — | GWAS association (p=1.0e-32) | Major Consortium Study |
| rs3764261 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs17091905 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs6073958 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs17489373 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs9939224 | CETP | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs5882 | CETP | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs1800777 | CETP | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs261290 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs2740488 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs261291 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs821840 | CETP | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs56156922 | — | GWAS association (p=0.0e+00) | Major Consortium Study |
| rs9987289 | LOC157273 | GWAS association (p=6.0e-25) | Major Consortium Study |
| rs247616 | — | GWAS association (p=1.0e-23) | Major Consortium Study |
| rs10468017 | — | GWAS association (p=8.0e-23) | Major Consortium Study |
| rs2043082 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs286 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs2169387 | — | GWAS association (p=9.9e-324) | Major Consortium Study |
| rs247617 | — | GWAS association (p=3.0e-308) | Major Consortium Study |
| rs79407615 | — | GWAS association (p=3.0e-293) | Major Consortium Study |
| rs56208677 | — | GWAS association (p=4.0e-279) | Major Consortium Study |
| rs72836561 | — | GWAS association (p=3.0e-275) | Major Consortium Study |
| rs11855284 | — | GWAS association (p=7.0e-255) | Major Consortium Study |
| rs79600951 | NUP93 | GWAS association (p=2.0e-235) | Major Consortium Study |
| rs268 | LPL | GWAS association (p=7.0e-220) | Major Consortium Study |
| rs539030095 | PAFAH1B2 | GWAS association (p=3.0e-210) | Major Consortium Study |
| rs6499862 | — | GWAS association (p=8.0e-187) | Major Consortium Study |
| rs3184504 | SH2B3 | GWAS association (p=1.0e-179) | Major Consortium Study |
| rs4841132 | LOC157273 | GWAS association (p=2.0e-169) | Major Consortium Study |
| rs4149307 | — | GWAS association (p=2.0e-162) | Major Consortium Study |
| rs5883 | CETP | GWAS association (p=4.0e-153) | Major Consortium Study |
| rs2278426 | ANGPTL8 | GWAS association (p=5.0e-153) | Major Consortium Study |
| rs2217332 | HERPUD1 | GWAS association (p=4.0e-147) | Major Consortium Study |
| rs192489212 | CEP164 | GWAS association (p=1.0e-144) | Major Consortium Study |
| rs2266788 | ZPR1 | GWAS association (p=3.0e-138) | Major Consortium Study |
| rs7528419 | CELSR2 | GWAS association (p=3.0e-137) | Major Consortium Study |
| rs13330096 | — | GWAS association (p=3.0e-135) | Major Consortium Study |
| rs138326449 | APOC3 | GWAS association (p=5.0e-134) | Major Consortium Study |
| rs174564 | FADS2 | GWAS association (p=1.0e-129) | Major Consortium Study |
| rs375372 | — | GWAS association (p=7.0e-122) | Major Consortium Study |
| rs673548 | APOB | GWAS association (p=2.0e-119) | Major Consortium Study |
| rs769449 | APOE | GWAS association (p=4.0e-114) | Major Consortium Study |
| rs11632618 | — | GWAS association (p=1.0e-107) | Major Consortium Study |
| rs55747707 | MLXIPL | GWAS association (p=4.0e-107) | Major Consortium Study |
| rs1052373 | MYBPC3 | GWAS association (p=1.0e-106) | Major Consortium Study |
| rs1801177 | LPL | GWAS association (p=4.0e-106) | Major Consortium Study |
| rs4420638 | APOC1 | GWAS association (p=4.0e-21) | Major Consortium Study |
| rs2943653 | — | GWAS association (p=2.0e-100) | Major Consortium Study |
| rs3135506 | APOA5 | GWAS association (p=9.0e-98) | Major Consortium Study |
| rs10773112 | — | GWAS association (p=7.0e-96) | Major Consortium Study |
| rs76868109 | — | GWAS association (p=2.0e-95) | Major Consortium Study |
| rs2254819 | ABCA1 | GWAS association (p=6.0e-95) | Major Consortium Study |
| rs56070533 | — | GWAS association (p=9.0e-95) | Major Consortium Study |
| rs983309 | — | GWAS association (p=7.0e-91) | Major Consortium Study |
| rs4846905 | — | GWAS association (p=8.0e-90) | Major Consortium Study |
| rs35797045 | SLC12A3 | GWAS association (p=3.0e-89) | Major Consortium Study |
| rs80175721 | — | GWAS association (p=1.0e-88) | Major Consortium Study |
| rs10096633 | — | GWAS association (p=2.0e-09) | Major Consortium Study |
| rs3779879 | TRPS1 | GWAS association (p=1.0e-87) | Major Consortium Study |
| rs75218485 | — | GWAS association (p=1.0e-86) | Major Consortium Study |
| rs3768321 | — | GWAS association (p=2.0e-81) | Major Consortium Study |
| rs2494748 | AKT1 | GWAS association (p=2.0e-81) | Major Consortium Study |
| rs186808413 | PAFAH1B2 | GWAS association (p=5.0e-81) | Major Consortium Study |
| rs12721043 | APOA4 | GWAS association (p=9.0e-81) | Major Consortium Study |
| rs12934552 | — | GWAS association (p=9.0e-81) | Major Consortium Study |
| rs1441778 | — | GWAS association (p=1.0e-80) | Major Consortium Study |
| rs13301006 | — | GWAS association (p=5.0e-80) | Major Consortium Study |
| rs76729986 | NUP93 | GWAS association (p=8.0e-79) | Major Consortium Study |
| rs2203452 | — | GWAS association (p=6.0e-76) | Major Consortium Study |
| rs2144300 | GALNT2 | GWAS association (p=3.0e-14) | Major Consortium Study |
| rs16942887 | PSKH1 | GWAS association (p=8.0e-33) | Major Consortium Study |
| rs55707100 | — | GWAS association (p=1.0e-72) | Major Consortium Study |
| rs2269434 | MYBPC3 | GWAS association (p=4.0e-72) | Major Consortium Study |
Showing the top 100 of 4,133 variants by evidence strength.
Associations aggregated from the GWAS Catalog and curated literature. Informational only — not medical advice.