ANGPTL8
angiopoietin like 8
Summary
Predicted to enable hormone activity. Involved in regulation of lipid metabolic process and triglyceride homeostasis. Acts upstream of or within positive regulation of protein processing and regulation of lipoprotein metabolic process. Located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]
Known Variants7 total
| rsid | Position (GRCh37) | Alleles | Class | ClinVar |
|---|---|---|---|---|
| rs1541924 | 19:11,350,189 | T/C | regulatory region variant | — |
| rs59168178 | 19:11,350,326 | G/A | missense variant | — |
| rs1329319448 | 19:11,350,477 | C/T | — | uncertain significance |
| rs2278426 | 19:11,350,488 | C/T | missense variant | — |
| rs752084449 | 19:11,350,528 | G/A | — | uncertain significance |
| rs145464906 | 19:11,350,874 | C/T | stop gained | — |
| rs777745739 | 19:11,350,877 | G/C | — | uncertain significance |
Gene information from NCBI Gene. Variant classifications from ClinVar.