rs2238675
▶GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
GWAS Catalog Trait Associations (4)
Genome-wide significant associations (p < 5×10⁻⁸) from the NHGRI-EBI GWAS Catalog.
triglyceride measurement
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele C
OR —
β 0.060
p 3.0e-16
N 94,674
Large GWAS
multi-ancestry
total cholesterol measurement
Below JE et al. “Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.” Scientific Reports 6:19429 (2016)
Allele C
OR 0.16
p 1.0e-13
N 4,383
Meta-analysis
multi-ancestry
Hoffmann TJ et al. “A large electronic-health-record-based genome-wide study of serum lipids.” Nature Genetics 50(3):401-413 (2018)
Allele C
OR —
β 0.051
p 2.0e-10
N 94,674
Large GWAS
multi-ancestry
non-high density lipoprotein cholesterol measurement
Graham SE et al. “The power of genetic diversity in genome-wide association studies of lipids.” Nature 600(7890):675-679 (2021)
Allele T
OR 0.16
p 7.0e-12
N 48,057
Large GWAS
Hispanic or Latin American
low density lipoprotein cholesterol measurement
Below JE et al. “Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.” Scientific Reports 6:19429 (2016)
Allele C
OR 0.13
p 2.0e-8
N 4,383
Meta-analysis
multi-ancestry
This variant is in our database but has no known associations or PRS memberships yet.
Gene information from NCBI Gene. Variant classifications from ClinVar.
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